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Cloning of a nuclear gene MRS1 involved in the excision of a single group I intron (bI3) from the mitochondrial COB transcript in S. cerevisiae
SummaryThe respiratory deficient yeast nuclear mutant MK3 is defective in the synthesis of the mature transcripts of the mitochondrial COB and OX13 genes, which code for apocytochrome b and subunit IExpand
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Association of cytochrome b translational activator proteins with the mitochondrial membrane: implications for cytochrome b expression in yeast
SummaryThe products of the nuclear genes CBS1 and CBS2 are both required for translational activation of mitochondrial apocytochrome b in yeast. We report the intramitochondrial localization of bothExpand
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Suppression of the Yeast Mutation rft1-1 by Human p53 (*)
Mutations in the gene encoding p53 have been found to be the most common genetic alterations in human cancer. p53 is thought to exert its function of tumor suppression through inhibition of cellExpand
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Mitochondrial suppression of a yeast nuclear mutation which affects the translation of the mitochondrial apocytochrome b transcript
SummaryWe describe a mitochondrial suppressor mutation, which restores respiratory competence to the nuclear pet−-mutant MK2. This mutant lacks the message of the mitochondrialcob-gene and insteadExpand
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In vitro and in vivo studies on the mitochondrial import of CBS1, a translational activator of cytochrome b in yeast
SummaryTranslation of mitochondrial cytochrome b mRNA in yeast is activated by the product of the nuclear gene CBS1. CBS1 encodes a 27 kDa precursor protein, which is cleaved to a 24 kDa matureExpand
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Over-expression, purification and determination of the proteolytic processing site of the yeast mitochondrial CBS1 protein
SummaryYeast transformats harboring the CBS1 gene under the control of the strong ADC1 promoter on a high copy number plasmid express the mitochondrial CBS1 protein at artificially high levels.Expand
DIE EISENBAHNBRUECKE UEBER DEN FIRTH OF FORTH IN SCHOTTLAND
DIE TECHNIK UND KONSTRUKTION DER FAST 100-JAEHRIGEN BRUECKE, DIE ENORME WIRTSCHAFTLICHE UND VERKEHRSTECHNISCHE VERBESSERUNGEN FUER SCHOTTLAND BRACHTE, SIND WENIG BEKANNT. DIE EIGENTLICHE BRUECKEExpand