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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016
Objective: To provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012.” Design: A consensus committee of 55 international experts representing 25… Expand
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
ObjectiveTo provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012”.DesignA consensus committee of 55 international experts representing 25… Expand
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
- A. Jones, N. Shapiro, S. Trzeciak, R. Arnold, Heather A. Claremont, J. Kline
- 24 February 2010
CONTEXT Goal-directed resuscitation for severe sepsis and septic shock has been reported to reduce mortality when applied in the emergency department. OBJECTIVE To test the hypothesis of… Expand
Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality.
CONTEXT Laboratory investigations suggest that exposure to hyperoxia after resuscitation from cardiac arrest may worsen anoxic brain injury; however, clinical data are lacking. OBJECTIVE To test… Expand
The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation*
Objectives:Organ failure worsens outcome in sepsis. The Sequential Organ Failure Assessment (SOFA) score numerically quantifies the number and severity of failed organs. We examined the utility of… Expand
MULTICENTER STUDY OF EARLY LACTATE CLEARANCE AS A DETERMINANT OF SURVIVAL IN PATIENTS WITH PRESUMED SEPSIS
We sought to determine (a) if early lactate clearance is associated with improved survival in emergency department patients with severe sepsis and (b) the concordance between central venous oxygen… Expand
Proof of principle: The predisposition, infection, response, organ failure sepsis staging system*
- M. Howell, D. Talmor, P. Schuetz, S. Hunziker, A. Jones, N. Shapiro
- Critical care medicine
- 1 February 2011
Objective:In an effort to improve upon the traditional sepsis syndrome definitions, the predisposition, infection, response, organ dysfunction (PIRO) model was proposed to better characterize sepsis.… Expand
Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol*
Objective:We sought to determine the association between time to initial antibiotics and mortality of patients with septic shock treated with an emergency department-based early resuscitation… Expand
Multicenter study of central venous oxygen saturation (ScvO(2)) as a predictor of mortality in patients with sepsis.
- J. Pope, A. Jones, D. Gaieski, R. Arnold, S. Trzeciak, N. Shapiro
- Annals of emergency medicine
STUDY OBJECTIVE Abnormal (both low and high) central venous saturation (ScvO(2)) is associated with increased mortality in emergency department (ED) patients with suspected sepsis. METHODS This was… Expand
Incidence of contrast-induced nephropathy after contrast-enhanced computed tomography in the outpatient setting.
- A. M. Mitchell, A. Jones, J. Tumlin, J. Kline
- Clinical journal of the American Society of…
BACKGROUND AND OBJECTIVES No prospective study has reported the incidence of contrast-induced nephropathy (CIN) or the associated morbidity and mortality after contrast-enhanced computed tomography… Expand