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Amphipathic solvation of indole: implications for the role of tryptophan in membrane proteins.
The microscopic structure of the tryptophan side chain, indole, in an amphiphilic environment has been investigated using a combination of neutron diffraction measurements and simulations inExpand
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On the atomic structure of cocaine in solution.
Cocaine is an amphiphilic drug which has the ability to cross the blood-brain barrier (BBB). Here, a combination of neutron diffraction and computation has been used to investigate the atomic scaleExpand
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On the positional and orientational order of water and methanol around indole: a study on the microscopic origin of solubility.
Although they are both highly polar liquids, there are a number of compounds, such as many pharmaceuticals, which show vastly different solubilities in methanol compared with water. From theories ofExpand
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Conformation and interactions of dopamine hydrochloride in solution.
The aqueous solution of dopamine hydrochloride has been investigated using neutron and X-ray total scattering data together with Monte-Carlo based modelling using Empirical Potential StructureExpand
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The solvation structure of alprazolam.
Alprazolam is a benzodiazepine that is commonly prescribed for the treatment of anxiety and other related disorders. Like other benzodiazepines, it is thought to exert its effect through interactionExpand
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On the structure of prilocaine in aqueous and amphiphilic solutions.
The solvation of prilocaine has been investigated in pure water and in an amphiphilic methanol/water solution using a combination of neutron diffraction with isotopic substitution augmented byExpand
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Oxford Twenty-first Century Approaches to Literature: Middle English, ed. Paul Strohm
The last decade has seen a rare effusion of guides and companions to medieval and, especially, Middle English literature, as well as to individual genres and authors of that period. Paul Strohm hasExpand
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