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Characterization of a novel prokaryotic GDP dissociation inhibitor domain from the G protein coupled membrane protein FeoB.
The FeoB family of membrane embedded G proteins are involved with high affinity Fe(II) uptake in prokaryotes. Here, we report that FeoB harbors a novel GDP dissociation inhibitor-like domain thatExpand
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Metastatic Bone Pain Palliation using 177Lu-Ethylenediaminetetramethylene Phosphonic Acid
177 Lu-ethylenediaminetetramethylene phosphonic acid (EDTMP) is presently suggested as an excellent bone seeking radionuclide for developing metastatic bone pain (MBP) palliation agent owing to itsExpand
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Production, Quality Control and Pharmacokinetic Studies of 166Ho-EDTMP for Therapeutic Applications
166Ho-EDTMP is a major therapeutic agent which is widely used in bone palliation therapy. In this study, a 166Ho-EDTMP complex was prepared successfully using an in-house synthesized EDTMP ligand andExpand
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An overview of copper radionuclides and production of 61Cu by proton irradiation of (nat)Zn at a medical cyclotron.
In this article, production methods and applications of copper radionuclides are overviewed with special attention toward (61)Cu, due to its interesting nuclear properties. Selection of productionExpand
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Development of [111In]-DTPA-buserelin for GnRH receptor studies
Abstract Buserelin was successively labeled with [111In]-Indium chloride after residuation with DTPA-dianhydride. Radio-chromatography showed an overall radiochemical purity of >90% (RTLC) and >95%Expand
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Production, Quality Control and Pharmacokinetic Studies of 177Lu-EDTMP for Human Bone Pain Palliation Therapy Trials
Developing new bone pain palliation agents is a mandate in handling end-stage cancer patients around the world. Possibly, Lu-177 ethylenediaminetetramethylene phosphonic acid (177Lu-EDTMP) is aExpand
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Assessment of effective absorbed dose of (111)In-DTPA-Buserelin in human on the basis of biodistribution rat data.
In this study, the effective absorbed dose to human organs was estimated, following intra vascular administration of (111)In-DTPA-Buserelin using biodistribution data from rats. Rats were sacrificedExpand
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Production, quality control and biodistribution studies of thulium-170-labeled ethylenediamine (tetramethylene phosphonic acid)
Abstract Thulium-170 (T1/2 = 128.4 d, Eβ (max) = 968 keV, Eγ = 84 keV (3.26%)) has radionuclidic properties suitable to be used in palliative therapy of bone metastases as an alternative to 89SrCl2.Expand
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Determination of human absorbed dose of 67GA-DTPA-ACTH based on distribution data in rats.
The absorbed radiation dose to human organs has been estimated, following intravenous administration of (67)Ga-labelled adrenocorticotrophic hormone (ACTH) using distribution data from injectedExpand
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Preparation of [66Ga]bleomycin complex as a possible PET radiopharmaceutical
SummaryGallium-66 (T1/2 = 9.49 h) is an interesting radionuclide that has potential use for positron emission tomography (PET) imaging of biological processes in intermediate to slow target tissueExpand
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