Share This Author
Telomeric Expression Sites Are Highly Conserved in Trypanosoma brucei
Phylogenetic analysis of constituent ESAG families suggests that BESs are sequence mosaics and that extensive recombination has shaped the evolution of the BES repertoire, a widely used strategy for immune evasion in pathogens, and telomere biology.
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila.
It is proposed that muscle amphiphysin is not involved in clathrin-mediated endocytosis, but in the structural organization of the membrane-bound compartments of the excitation-contraction coupling machinery of muscles.
GeneDB—an annotation database for pathogens
GeneDB (http://www.genedb.org) is a genome database for prokaryotic and eukaryotic pathogens and closely related organisms that combines data from completed and ongoing genome projects with curated annotation, which is readily accessible from a web based resource.
A comprehensive evaluation of rodent malaria parasite genomes and gene expression
The greatly improved genome assemblies of PbA and PcAS, newly sequenced the virulent parasite P. yoelii YM genome, sequenced additional RMP isolates/lines and have characterized genotypic diversity within RMP species.
The genome of the simian and human malaria parasite Plasmodium knowlesi
This is the first monkey malaria parasite genome to be described, and it provides an opportunity for comparison with the recently completed P. vivax genome and other sequenced Plasmodium genomes.
Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement
BackgroundRhs genes are prominent features of bacterial genomes that have previously been implicated in genomic rearrangements in E. coli. By comparing rhs repertoires across the Enterobacteriaceae,…
A RECONCILIATION ANALYSIS OF HOST SWITCHING IN PLANT‐FUNGAL SYMBIOSES
- A. Jackson
- BiologyEvolution; international journal of organic…
- 1 September 2004
According to reconciliation analysis, the contribution of host phylogeny varies widely across plant‐fungal symbioses, making host specificity and coad‐aptation poor indicators of macroevolutionary trends because they are necessary, but not sufficient, conditions.
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans.
The results suggest that the recent evolutionary histories of C. albicans and C. dubliniensis are quite different, with the former having lost genomic capacity and key pathogenic functions, and the latter being a significantly less virulent and less versatile pathogen.
The Evolution of Amastin Surface Glycoproteins in Trypanosomatid Parasites
- A. Jackson
- BiologyMolecular biology and evolution
- 11 September 2009
A substantial elaboration of amastin repertoire directly associated with the origin of Leishmania is described, suggesting that some amastIn genes evolved novel functions crucial to cell function in leishmanial parasites after the acquisition of a vertebrate host.
A Cell-surface Phylome for African Trypanosomes
- A. Jackson, Harriet C Allison, J. Barry, Mark C. Field, C. Hertz-Fowler, M. Berriman
- BiologyPLoS neglected tropical diseases
- 1 March 2013
The cell surface phylome (CSP) is created by estimating phylogenies for 79 gene families with putative surface functions to understand the more recent evolution of African trypanosome surface architecture and presents the first global picture of the origins and dynamics of cell surface architecture in Africantrypanosomes.