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Activation of Progelatinase A by Mammalian Legumain, a Recently Discovered Cysteine Proteinase
TLDR
It is concluded that legumain is clearly capable of processing progelatinase A to the active enzyme in vitro and in cultured cells.
Cathepsin D. Characteristics of immunoinhibition and the confirmation of a role in cartilage breakdown.
TLDR
The antisera produced up to 90% inhibition of the autolysis of cartilage from chicks and rabbits, indicating that cathepsin D is the enzyme mainly responsible for the breakdown of proteoglycans in this system.
Physical and Laboratory Characteristics of Heterozygote Carriers of the Fanconi Aplasia Gene
TLDR
The results suggest that heterozygotes show minor physical and haematological abnormalities consistent with partial expression of the Fanconi gene in the heterozygote.
Subcellular distribution of lead in the rat.
TLDR
As the changes induced in the lead concentration of tissues were subtoxic, it is suggested that the observed differences in the binding of lead to particular fractions may represent normal turnover.
THE IMMUNOCYTOCHEMICAL DEMONSTRATION OF CATHEPSIN D
Cathepsin D has been demonstrated for the first time using an immunocytochemical approach and fluorescence microscopy. It has been localized in chick epithelium-like cells and in cells of synovia
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