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HIV‐1 regulation of latency in the monocyte‐macrophage lineage and in CD4+ T lymphocytes
The introduction in 1996 of the HAART raised hopes for the eradication of HIV‐1. Unfortunately, the discovery of latent HIV‐1 reservoirs in CD4+ T cells and in the monocyte‐macrophage lineage provedExpand
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Achieving a cure for HIV infection: do we have reasons to be optimistic?
The introduction of highly active antiretroviral therapy (HAART) in 1996 has transformed a lethal disease to a chronic pathology with a dramatic decrease in mortality and morbidity of AIDS-relatedExpand
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Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons
The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about theExpand
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Shank3-Rich2 Interaction Regulates AMPA Receptor Recycling and Synaptic Long-Term Potentiation
Synaptic long-term potentiation (LTP) is a key mechanism involved in learning and memory, and its alteration is associated with mental disorders. Shank3 is a major postsynaptic scaffolding proteinExpand
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Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication
The Human Phosphate-Binding protein (HPBP) is a serendipitously discovered lipoprotein that binds phosphate with high affinity. HPBP belongs to the DING protein family, involved in various biologicalExpand
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Carbachol induces homologous steroidogenic refractoriness of bovine fasciculata-reticularis cells
Recently it was shown that the cholinergic agonist carbachol stimulates cortisol production in bovine ZFR cells via muscarinic receptor M(3). In the present study, we investigated the effect ofExpand
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