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Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology
The aim of this article is to outline the rationale for, and the expectations of, the BJP with respect to work published in the Journal that includes immunoblotting or immunohistochemical data and to reduce potential misinterpretations and to maximise the communication and transparency of essential information.
ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
The BJP has been and remains an active advocate of the ARRIVE guidelines and the Editor in Chief of the BJP is a member of the new team that was assembled, which triggered a reappraisal of the guidelines led by the NC3Rs who, in 2018, established a new, international Working Group to review and update the ARrIVE guidelines.
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
A multistage tuberculosis vaccine that confers efficient protection before and after exposure
A multistage vaccination strategy in which the early antigens Ag85B and 6-kDa early secretory antigenic target (ESAT-6) are combined with the latency-associated protein Rv2660c (H56 vaccine), which confers protective immunity characterized by a more efficient containment of late-stage infection.
Flavonoids: old and new aspects of a class of natural therapeutic drugs.
Cannabinoids and the gut: new developments and emerging concepts.
Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High‐fat Diet
In mice, endocannabinoids modulate insulin release from pancreatic β‐cells and adipokine expression in adipocytes through cannabinoid receptors through cannabinoids receptors, and these alterations are elevated during hyperglycemia and obesity.
Polyphenols: A concise overview on the chemistry, occurrence, and human health
This review gives an updated picture of each class of phenolic compounds and their properties and the use of current existing databases of bioactive compounds including polyphenols is described as key tools for human health research.
Cannabinoid CB1‐receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation
It is concluded that inflammation of the gut increases the potency of cannabinoid agonists possibly by ‘up‐regulating’ CB1 receptor expression; in addition, endocannabinoids, whose turnover is increased in inflamed gut, might tonically inhibit intestinal motility.
Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2.
Induction of intestinal growth by GLP-2 in wild-type mice results in a normal-to-increased capacity for nutrient digestion and absorption in vivo.