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Two‐Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure
In patients with advanced heart failure, a fully magnetically levitated centrifugal‐flow pump was superior to a mechanical‐bearing axial‐ flow pump with regard to survival free of disabling stroke or reoperation to replace or remove a malfunctioning device. Expand
A Fully Magnetically Levitated Circulatory Pump for Advanced Heart Failure
Among patients with advanced heart failure, implantation of a fully magnetically levitated centrifugal‐flow pump was associated with better outcomes at 6 months than was implanted of an axial‐ flow pump, primarily because of the lower rate of reoperation for pump malfunction. Expand
The presence of two local myocardial sheet populations confirmed by diffusion tensor MRI and histological validation
- Geoffrey L. Kung, Tom C. Nguyen, +4 authors D. Ennis
- Physics, Medicine
- Journal of magnetic resonance imaging : JMRI
- 1 November 2011
To establish the correspondence between the two histologically observable and diffusion tensor MRI (DTMRI) measurements of myolaminae orientation for the first time and show that single myolaminar… Expand
A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report
- M. Mehra, N. Uriel, +37 authors D. Goldstein
- The New England journal of medicine
- 17 March 2019
Among patients with advanced heart failure, a fully magnetically levitated centrifugal‐flow left ventricular assist device was associated with less frequent need for pump replacement than an axial‐flow device and was superior with respect to survival free of disabling stroke or reoperation to replace or remove a malfunctioning device. Expand
The impact of mitral valve surgery combined with maze procedure.
- A. Itoh, J. Kobayashi, +5 authors S. Kitamura
- European journal of cardio-thoracic surgery…
- 1 June 2006
The large left atrium, small f-wave, and long AF duration were significant risk factors for failed maze procedures, suggesting that earlier surgical interventions would result in superior results in mitral valve surgery combined with maze procedure. Expand
The Human Heart Contains Distinct Macrophage Subsets with Divergent Origins and Functions
Study of macrophage heterogeneity in human hearts reveals a subset of inflammatory macrophages that is associated with cardiac dysfunction in patients with heart failure, and provides initial evidence for the functional importance of macrophic heterogeneity in the human heart. Expand
Left Ventricular Unloading by Impella Device Versus Surgical Vent During Extracorporeal Life Support.
PVAD use in ECLS patients is an effective means of LV unloading and preventing worsened pulmonary edema, with outcomes and complications that are comparable to surgical LV vent. Expand
Stress-strain behavior of mitral valve leaflets in the beating ovine heart.
- G. Krishnamurthy, A. Itoh, +5 authors N. B. Ingels
- Materials Science, Medicine
- Journal of biomechanics
- 25 August 2009
In inverse finite element (FE) analysis, the AML, in vivo, operates linearly over a physiologic range of pressures in the closed mitral valve, unlike isolated leaflets. Expand
Active stiffening of mitral valve leaflets in the beating heart.
- A. Itoh, G. Krishnamurthy, +7 authors N. B. Ingels
- American journal of physiology. Heart and…
- 1 June 2009
The anterior leaflet of the mitral valve, viewed traditionally as a passive membrane, is shown to be a highly active structure in the beating heart, raising the possibility that these leaflets are neurally controlled tissues, with potentially adaptive capabilities to meet the changing physiological demands on the heart. Expand
Concomitant aortic valve procedures in patients undergoing implantation of continuous-flow left ventricular assist devices: An INTERMACS database analysis.
- Jason O. Robertson, D. Naftel, +6 authors S. Silvestry
- The Journal of heart and lung transplantation…
- 1 June 2015
AV closure was associated with increased mortality when compared with repair or replacement in patients with existing aortic insufficiency who underwent LVAD insertion, and the reasons for this association require further investigation. Expand