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Asymptomatic brain magnetic resonance imaging abnormalities in splenectomized adults with thalassemia intermedia
Summary.  Background: A high incidence of thrombotic events in thalassemia intermedia (TI) patients led to the identification of a hypercoagulable state. Brain involvement has not been widely studiedExpand
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Correlation of liver iron concentration determined by R2 magnetic resonance imaging with serum ferritin in patients with thalassemia intermedia
Thalassemia intermedia is a highly diverse group of thalassemia syndromes associated with anemia and a range of specific complications, such as extramedullary hematopoiesis, leg ulcers, gallstonesExpand
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Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations
The human leucocyte antigen (HLA) system shows extensive variation in the number and function of loci and the number of alleles present at any one locus. Allele distribution has been analysed in manyExpand
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Pregnancy in patients with β‐thalassemia intermedia: Outcome of mothers and newborns
Little is known about the outcome of pregnancy in women with β‐thalassemia intermedia (TI). Over 10 years, maternal and neonatal outcomes of women with TI followed at a single thalassemia center wereExpand
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Sickle cell disease: the Lebanese experience
Sickle cell disease (SCD), the commonest single gene disorder worldwide, is an inherited disease that has different clinical and hematological manifestations in different populations. The objectiveExpand
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Pregnancy in patients with beta-thalassemia intermedia: outcome of mothers and newborns.
Little is known about the outcome of pregnancy in women with beta-thalassemia intermedia (TI). Over 10 years, maternal and neonatal outcomes of women with TI followed at a single thalassemia centerExpand
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Levels of non‐transferrin‐bound iron as an index of iron overload in patients with thalassaemia intermedia
Non‐transferrin‐bound iron (NTBI) was evaluated as an index of iron overload in a cross‐sectional randomised study in 74 non‐transfused patients with thalassaemia intermedia (TI). Mean NTBI (2·92 ±Expand
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Efficacy and tolerability of peginterferon alpha‐2a with or without ribavirin in thalassaemia major patients with chronic hepatitis C virus infection
Thalassaemia patients with genotype 1 or 4 chronic hepatitis C virus (HCV) infection were randomised to receive peginterferon alpha‐2a 180 mg/week ribavirin for 48 weeks. Primary efficacy variableExpand
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β‐Globin gene cluster haplotypes and HbF levels are not the only modulators of sickle cell disease in Lebanon
Abstract: Sickle cell disease (SCD) is an inherited autosomal recessive disorder of the β‐globin chain. Despite the fact that all subjects with SCD have the same single base pair mutation, theExpand
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Intravenous zoledronic acid treatment in thalassemia-induced osteoporosis: results of a phase II clinical trial
Osteoporosis is an important cause of morbidity in beta-thalassemia patients. Bisphosphonates have been recently used for the treatment of osteoporosis in beta-thalassemia. This study is aExpand
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