The hyperuricemia of gout of necessity results from either an excessive production of uric acid or a diminished elimination of uric acid either by the kidney or by means of uricolysis. Behind the… (More)
Antibody levels to 12 different pneumococcal capsular polysaccharides as well as the combined mean antibody level were measured in 19 patients with systemic lupus erythematosus (SLE) at 1, 2 and 3… (More)
Peripheral blood mononuclear cells (PBMC) of normal human donors are spontaneously cytotoxic for certain tumour-derived and virus-infected target cells. This so-called natural killing (NK) can be… (More)
PURPOSE
We compared the long-term outcome of patients with lupus nephritis in whom normalization of complement levels (CH50) was sustained by adjustment of immunosuppressive therapy to those patients… (More)
Forty-three patients known to have systemic lupus erythematosus (SLE) underwent pulmonary function evaluation. Pulmonary dysfunction was noted in 38 patients (88%). The most common abnormality was an… (More)
A substantial number of patients with gout has been shown to produce excessive amounts of uric acid (1-4). This overproduction has been demonstrated by the excretion of greater than normal amounts of… (More)