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Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedy
TLDR
Bioassay-guided fractionation of extracts of Toddalia asiatica, a plant used by the Pokot tribe of Kenya to treat fevers, has yielded the alkaloid nitidine as the major antimalarial component, and results show a lack of cross-resistance between chloroquine and nitidine.
Natural Products Isolation
TLDR
Natural Product Isolation: An Overview Satyajit D. Sarker and Lutfun Nahar Purification by Solvent Extraction Using Partition Coefficient Hideaki Otsuka Crystallization in Final Stages of Purification.
Fucosterol inhibits the cholinesterase activities and reduces the release of pro-inflammatory mediators in lipopolysaccharide and amyloid-induced microglial cells
TLDR
Insight is provided into the development of fucosterol as a potential drug candidate for AD, a multifactorial neurodegenerative disorder by providing protective effects against Aβ-mediated neuroinflammation by inhibiting the production of pro-inflammatory mediators.
The essential oil from Heteropyxis natalensis harv: Its antimicrobial activities and phytoconstituents
TLDR
The essential oil obtained from Heteropyxis natalensis by steam distillation was tested for antimicrobial properties and indicated the essential oil contained 1,8-cineole, limonene, β-myrcene, α-phellandrene and α-pinene.
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