• Publications
  • Influence
Retinotopy and Functional Subdivision of Human Areas MT and MST
TLDR
Using stimuli designed to tease apart differences in retinotopic organization and receptive field size, a double dissociation is established between two distinct MT+ subregions in 8 of the 10 hemispheres studied. Expand
The effect of stimulus strength on the speed and accuracy of a perceptual decision.
TLDR
A theory of perceptual decision making based on a diffusion model that accounts for response time and accuracy as a function of both stimulus strength and speed-accuracy instructions and subsume the predictions of Piéron's Law. Expand
Neural Activity in Macaque Parietal Cortex Reflects Temporal Integration of Visual Motion Signals during Perceptual Decision Making
  • A. Huk, M. Shadlen
  • Psychology, Medicine
  • The Journal of Neuroscience
  • 9 November 2005
TLDR
Results demonstrate that LIP is involved in neural time integration underlying the accumulation of evidence in this task, and suggest that decision-related LIP responses, as well as behavioral choices and reaction times, can be explained by near-perfect time integration that stops when a criterion amount of evidence has been accumulated. Expand
Spikes versus BOLD: what does neuroimaging tell us about neuronal activity?
By demonstrating that fMRI responses in human MT+ increase linearly with motion coherence and comparing these responses with slopes of single-neuron firing rates in monkey MT, a new paper providesExpand
Encoding and decoding in parietal cortex during sensorimotor decision-making
TLDR
This work examined the neural code in LIP at the level of individual spike trains using a statistical approach based on generalized linear models and derived an optimal decoder for heterogeneous, multiplexed LIP responses that could be implemented in biologically plausible circuits. Expand
Neuronal Basis of the Motion Aftereffect Reconsidered
Several fMRI studies have reported MT+ response increases correlated with perception of the motion aftereffect (MAE). However, attention can strongly affect MT+ responses, and subjects may naturallyExpand
Pattern-motion responses in human visual cortex
TLDR
Reducing the perceptual coherence of the plaids yielded a corresponding decrease in pattern-motion responsivity, providing evidence that percepts of coherent motion are closely linked to the activity of pattern- motion cells in human MT+. Expand
Single-trial spike trains in parietal cortex reveal discrete steps during decision-making
TLDR
Examination of single-trial responses in LIP using statistical methods for fitting and comparing latent dynamical spike-train models found that choice-selective neurons were better described by the stepping model, and the inferred steps carried more information about the animal’s choice than spike counts. Expand
Neural Circuit Dynamics Underlying Accumulation of Time-Varying Evidence During Perceptual Decision Making
TLDR
A recurrent neural circuit model is used to simulate an experiment in which monkeys performed a direction-discrimination task on a visual motion stimulus, and shows further support for an attractor network model of time integration in perceptual decision making. Expand
Dissociated functional significance of decision-related activity in the primate dorsal stream
During decision making, neurons in multiple brain regions exhibit responses that are correlated with decisions. However, it remains uncertain whether or not various forms of decision-related activityExpand
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