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Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
TLDR
The pathological findings in 100 patients diagnosed prospectively by a group of consultant neurologists as having idiopathic Parkinson's disease are reported, and these observations call into question current concepts of Parkinson's Disease as a single distinct morbid entity. Expand
A clinicopathologic study of 100 cases of Parkinson's disease.
TLDR
The clinical details of 100 cases of histologically confirmed Parkinson's disease were examined and correlated with pathologic findings, finding the general pattern of disease conformed to traditional descriptions, and the findings broaden the present clinical and pathologic spectrum of Parkinson's Disease. Expand
Clinicopathological investigation of vascular parkinsonism, including clinical criteria for diagnosis
TLDR
New clinical criteria for a diagnosis of VP are proposed based on the clinicopathological findings of this study, and the clinical features at presentation varied according to the speed of onset and the underlying vascular pathological state. Expand
The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service.
TLDR
The clinical and pathological diagnoses of 143 cases of parkinsonism seen by neurologists associated with the movement disorders service at The National Hospital for Neurology and Neurosurgery in London suggest that neurologists with particular expertise in the field of movement disorders may be using a method of pattern recognition for diagnosis which goes beyond that inherent in any formal set of diagnostic criteria. Expand
What features improve the accuracy of clinical diagnosis in Parkinson's disease
TLDR
Assessment of clinical features of 100 patients diagnosed prospectively by a group of consultant neurologists as having idiopathic Parkinson's disease suggests that studies based on consultant diagnosis of PD, using standard diagnostic criteria, will include cases other than PD, thus distorting results from clinical trials and epidemiologic studies. Expand
Improved accuracy of clinical diagnosis of Lewy body Parkinson’s disease
TLDR
Assessment of the clinical features suggests that an accuracy of 90% may be the highest that can be expected using current diagnostic criteria for idiopathic PD. Expand
What features improve the accuracy of clinical diagnosis in Parkinson's disease: A clinicopathologic study
TLDR
Assessment of clinical features of 100 patients diagnosed prospectively by a group of consultant neurologists as having idiopathic Parkinson's disease suggests that studies based on consultant diagnosis of PD, using standard diagnostic criteria, will include cases other than PD, thus distorting results from clinical trials and epidemiologic studies. Expand
What clinical features are most useful to distinguish definite multiple system atrophy from Parkinson's disease?
TLDR
Predictive models may help differentiate MSA and PD premortem and poorly recognised features, suggestive of MSA, included preserved cognitive function and absence of psychiatric effects from antiparkinsonian medication. Expand
Voice characteristics in the progression of Parkinson's disease.
TLDR
The present data suggested that the PD patients' voices were characterized by excess jitter, a high-speaking fundamental frequency for males and a reduced fundamental frequency variability for females. Expand
Response of parkinsonian swallowing dysfunction to dopaminergic stimulation
TLDR
Findings suggest that parkinsonian swallowing dysfunction is not solely related to nigrostriatal dopamine deficiency and may be due to an additional non-dopamine related disturbance of the central pattern generator for swallowing in the pedunculopontine nucleus or related structures in the medulla. Expand
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