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Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p 1
Proteins essential for the assembly of functional peroxisomes are designated peroxins and are encoded by PEX genes. In yeast, Pex3p was previously identified as a peroxisomal integral membraneExpand
Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.
Inherited defects in the peroxisomal ATP-binding cassette (ABC) transporter adrenoleukodystrophy protein (ALDP) lead to the lethal peroxisomal disorder X-linked adrenoleukodystrophy (X-ALD), forExpand
Algae and UV irradiation: effects on ultrastructure and related metabolic functions.
The effects of ultraviolet radiation in the biological relevant wavebands of UV-A (315-400 nm) and UV-B (280-315 nm) on algae have become an important issue as a man-made depletion of the protectingExpand
Investigating cytoskeletal function in chloroplast protrusion formation in the arctic-alpine plant Oxyria digyna.
Arctic and alpine plants like Oxyria digyna have to face enhanced environmental stress. This study compared leaves from Oxyria digyna collected in the Arctic at Svalbard (78 degrees N) and in theExpand
Temperature-sensitive formation of chloroplast protrusions and stromules in mesophyll cells of Arabidopsis thaliana
Summary.In leaf mesophyll cells of transgenic Arabidopsis thaliana plants expressing GFP in the chloroplast, stromules (stroma-filled tubules) with a length of up to 20 μm and a diameter of aboutExpand
Ecophysiology and ultrastructure of Ancylonema nordenskiöldii (Zygnematales, Streptophyta), causing brown ice on glaciers in Svalbard (high arctic)
At the arctic archipelago of Svalbard, bare glacier surfaces are populated by microalgae like Ancylonema nordenskiöldii (Zygnematales, Streptophyta). The resulting blooms cause, due to a vacuolarExpand
Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis
Cystic fibrosis (CF) is the most common lethal inherited disease in Caucasians and is caused by mutations in the CFTR gene. The disease is incurable and medical treatment is limited to theExpand
The vegetative arctic freshwater green alga Zygnema is insensitive to experimental UV exposure.
The physiological performance and ultrastructural integrity of the vegetative freshwater green alga Zygnema sp., growing under ambient polar day solar radiation and after exposure to experimentallyExpand
Primary structure of human PMP69, a putative peroxisomal ABC-transporter.
We have cloned the cDNA of a novel human ABC-half-transporter highly similar to peroxisomal ABC-half-transporters such as the adrenoleukodystrophy protein (ALDP) and the peroxisomal protein 70Expand
Desiccation stress and tolerance in green algae: consequences for ultrastructure, physiological and molecular mechanisms
Although most green algae typically occur in aquatic ecosystems, many species also live partly or permanently under aeroterrestrial conditions, where the cells are exposed to the atmosphere and henceExpand