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Constipation and a low-fiber diet are not associated with diverticulosis.
- A. Peery, R. Sandler, +7 authors J. Baron
- Clinical gastroenterology and hepatology : the…
- 1 December 2013
BACKGROUND & AIMS Asymptomatic diverticulosis is commonly attributed to constipation caused by a low-fiber diet, although evidence for this mechanism is limited. We examined the associations between… Expand
Self-expanding plastic stents in treatment of benign esophageal conditions.
- A. Holm, J. G. de la Mora Levy, C. Gostout, M. Topazian, T. Baron
- Gastrointestinal endoscopy
BACKGROUND Recently, self-expanding plastic stents (SEPSs) have been proposed for the treatment of benign esophageal disease. OBJECTIVES Our purpose was to review our experience with SEPSs in… Expand
A mechanosensitive calcium channel in human intestinal smooth muscle cells.
- G. Farrugia, A. Holm, A. Rich, M. Sarr, J. Szurszewski, J. Rae
- Biology, Medicine
- 1 October 1999
BACKGROUND & AIMS Gastrointestinal smooth muscle strips devoid of enteric nerve cells can contract in response to stretch, suggesting that mechanosensitivity and mechanotransduction can occur at the… Expand
Sodium current in human jejunal circular smooth muscle cells.
BACKGROUND & AIMS Sodium channels are key regulators of neuronal and muscle excitability. However, sodium channels have not been definitively identified in gastrointestinal smooth muscle. The aim of… Expand
Cytoskeletal modulation of sodium current in human jejunal circular smooth muscle cells.
- P. Strege, A. Holm, +4 authors G. Farrugia
- Biology, Medicine
- American journal of physiology. Cell physiology
A Na(+) current is present in human jejunal circular smooth muscle cells. The aim of the present study was to determine the role of the cytoskeleton in the regulation of the Na(+) current. Whole cell… Expand
Species dependent expression of intestinal smooth muscle mechanosensitive sodium channels
- P. Strege, A. Mazzone, +7 authors G. Farrugia
- Biology, Medicine
- Neurogastroenterology and motility : the official…
- 1 February 2007
Abstract A mechanosensitive Na+ current carried by Nav1.5 is present in human intestinal circular smooth muscle and contributes to regulation of intestinal motor function. Expression of this channel… Expand
The Bedside Index for Severity in Acute Pancreatitis: a systematic review of prospective studies to determine predictive performance
- S. Chandra, A. Murali, R. Bansal, D. Agarwal, A. Holm
- Journal of community hospital internal medicine…
- 19 September 2017
ABSTRACT Background: predicting the development of severe disease has remained a major challenge in management of acute pancreatitis. The Bedside Index for Severity in Acute Pancreatitis (BISAP) is… Expand
What Should Be Done with a Dilated Bile Duct?
Current methods for imaging the biliary tree include ultrasound, CT, MRI, endoscopic retrograde cholangiography, and endoscopic ultrasound (EUS). Bile duct abnormalities may be identified during… Expand
Whole cell current and membrane potential regulation by a human smooth muscle mechanosensitive calcium channel.
- A. Holm, A. Rich, M. Sarr, G. Farrugia
- Chemistry, Medicine
- American journal of physiology. Gastrointestinal…
- 1 December 2000
Mechanotransduction is required for a wide variety of biological functions. The aim of this study was to determine the effect of activation of a mechanosensitive Ca(2+) channel, present in human… Expand
Palliative use of percutaneous endoscopic gastrostomy and percutaneous endoscopic cecostomy tubes.
Percutaneous endoscopic gastrostomy (PEG) tubes are most commonly placed for feeding purposes with the intention of maintenance or improvement in nutritional status; however, they may also be used in… Expand