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Neurochemical correlates of alcohol preference in inbred strains of mice
C57B1/6J, a specific inbred strain of mice with high alcohol preference and DBA/2J, a specific inbred strain with poor preference for alcohol were studied. Brain content of acetylcholine, uptake of… Expand
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
The objective of this study is to understand the mechanism underlying the cardioprotective effects of pinacidil, an ATP-sensitive K+ channel (K(ATP)) opener. We examined the effects of 10 microM… Expand
A simple purification of calmodulin by reversed phase chromatography with hydrophobic polymer 3520.
A new adsorption chromatography procedure for the purification of calmodulin from bovine brain was developed using polymeric adsorbent 3520. Calmodulin was first isolated by DEAE-Cellulose column… Expand
Experimental studies on alcoholism I. Increased in alcohol preference by 5,6-dihydroxytryptamine and brain acetylcholine
The effects of an intracisternal injection of 5,6-Dihydroxytryptamine (5,6-DHT; 75 Μg/rat) on alcohol preference were studied in rats. Results indicated that alcohol consumption was increased… Expand
Soybean metal-binding proteins : isolation of a phosphatase that inhibits calmodulin activity
Identification de proteines impliquees dans le metabolisme du phosphate et ayant une interaction avec la calmoduline dans des graines de soja germees ou des tourteaux non delipides. L'affinite pour… Expand
Phosphorylation of brain muscarinic receptor: evidence of receptor regulation.
- A. Ho, Q. Ling, R. Duffield, P. H. Lam, J. Wang
- Chemistry, Medicine
- Biochemical and biophysical research…
- 13 February 1987
Muscarinic receptor, from porcine synaptic membrane, was purified by affinity chromatography. Molecular weight analysis by SDS-gel electrophoresis revealed one major peptide with an apparent Mr of 68… Expand
INTERACTIONS OF NARCOTICS, NARCOTIC ANTAGONISTS, AND ETHANOL DURING ACUTE, CHRONIC, AND WITHDRAWAL STATES *
- A. Ho, Raymond C. A. Chen, J. Morrison
- Annals of the New York Academy of Sciences
- 1 December 1976
Interactions between narcotics and ethanol have been reported in human and in animal studies. Heroin addicts maintained on prolonged methadone treatment who became secondarily addicted to ethanol… Expand
Toxic interactions of ethanol with other central depressants: Antagonism by naloxone to narcosis and lethality
The effects of naloxone on narcosis and/or lethality induced by diazepam, lithium, methaqualone and phenobarbital either alone or in combination with ethanol were studied in mice. Interaction… Expand
Calmodulin regulation of cholinergic muscarinic receptor: effects of calcium and phosphorylating states.
Calmodulin (CaM) regulation of cholinergic muscarinic receptor was investigated using synaptic membrane isolated from rat brains and [3H]-QNB as a binding ligand. CaM exerts a biphasic effect on… Expand
Lithium and ethanol preference
LEVINE, B. B. (1961). SCHNEIDER, C. H. (1970). Editors: Stewart, G. T. & McGovern, J. P. SCHNEIDER, C. H. & DE WECK, A. L. (1968). SCHWARTZ, M. A. & Wu, G. M. (1966). SCHWARTZ, M. A. (1968). Zbid.,… Expand