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  • Johannes Hebebrand, Anke Hinney
  • Psychology, Medicine
  • Zeitschrift fur Kinder- und Jugendpsychiatrie und…
  • 2009 (First Publication: 1 July 2009)
  • • Worldwide obesity has nearly doubled since 1980. • In 2008, more than 1.4 billion adults, 20 and older, were overweight. Of these over 200 million men and nearly 300 million women were obese. • 35%Expand
  • A. Hinney, T. Bettecken, +15 authors J. Hebebrand
  • Medicine, Biology
  • The Journal of clinical endocrinology and…
  • 2006 (First Publication: 1 May 2006)
  • CONTEXT Autosomal dominant inheritance of mutations in the melanocortin-4 receptor gene (MC4R) is currently regarded as the most relevant genetic cause for extreme obesity and affects 2-4% ofExpand
  • A. Hinney, A. Schmidt, +11 authors J. Hebebrand
  • Medicine
  • The Journal of clinical endocrinology and…
  • 1999 (First Publication: 1 April 1999)
  • The melanocortin-4 receptor gene (MC4-R) has been implicated in weight regulation. Recently, two independent groups reported frameshift mutations associated with a dominant form of obesity (1, 2). WeExpand