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Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis.
BACKGROUND Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), a novel member of the tumor necrosis factor family, induces apoptosis in TRAIL-sensitive tumors through the activation of… Expand
Molecular Mechanisms Contributing to Necrotizing Enterocolitis
ObjectiveTo examine the cellular mechanisms involved in the pathogenesis of necrotizing enterocolitis (NEC). Summary Background DataNecrotizing enterocolitis is a major cause of death and… Expand
Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.
- A. Cabrales, Jeovanis Gil, +10 authors L. González
- Chemistry, Medicine
- European journal of pharmaceutical sciences…
- 23 January 2013
GHRP-6 is a growth hormone secretagogue that also enhances tissue viability in different organs. In the present work, we studied the pharmacokinetics of this short therapeutic hexapeptide… Expand
AMPLICOR MTB polymerase chain reaction test for identification of Mycobacterium tuberculosis in positive Difco ESP II broth cultures.
- A. Hernández, J. S. Bergmann, G. Woods
- Biology, Medicine
- Diagnostic microbiology and infectious disease
The reliability of the Roche AMPLICOR polymerase chain reaction (PCR) Mycobacterium tuberculosis (MTB) test for identification of M. tuberculosis complex (MTBC) in Difco ESP II broth cultures was… Expand
Assessment of Differential Gene Expression Patterns in Human Colon Cancers
ObjectiveTo use a novel genomic approach to determine differential gene expression patterns in colon cancers of different metastatic potential. Summary Background DataColorectal cancer is the third… Expand
Functional genomics: clinical effect and the evolving role of the surgeon.
The genetic and molecular revolution that has occurred over the last 2 decades has dramatically increased our understanding of basic disease processes and will undoubtedly lead to improved detection… Expand
Mitochondrial DNA damage and altered membrane potential (delta psi) in pancreatic acinar cells induced by reactive oxygen species.
BACKGROUND Reactive oxygen species (ROS) have been implicated in the induction of acute pancreatitis. Mitochondria possess a distinct genome (mtDNA) that is more susceptible to ROS-induced damage… Expand
Oxidation Reactions in 9a-Halosteroids by Jones Reagent
Current investigations guided to searching androstane derivatives with potential anabolic activity, weakly androgenic one directed us to synthesize 3b,11b-dihydroxy-9a-halo-5a-androstane- 17-ones… Expand
Characterization of two experimental rodent models for evaluating novel drugs for rheumatoid arthritis
Rodent models are widely used to evaluate molecular mechanisms of rheumatoid arthritis (RA) and potential new therapeutic drugs. In our context, we developed and characterized two experimental models… Expand
Influence of N at Different Partial Pressures During Growing TiN by PLD
This work presents the study of a TiNx thin films series, grown by PLD on Si (1 1 1) substrate at different conditions. Ti target was ablated in presence of a N2 atmosphere and a series of thin films… Expand