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Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
It is reported that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis, and it is interesting that ATGL contains a “patatin domain” common to plant acyl-hydrolases.
Oxidized phospholipids: from molecular properties to disease.
The molecular features that are essential for the understanding of the biological actions of pure oxidized phospholipids are highlighted and their chemical structures are described as a basis for an understanding of their physical and (bio)chemical properties in membrane- and protein-bound form.
The Kinetics of Phagosome Maturation as a Function of Phagosome/Lysosome Fusion and Acquisition of Hydrolytic Activity
Three novel assays that quantify important biological properties of the phagosome as it matures are described, demonstrating the veracity, sensitivity and versatility of the assays.
The 6-a-day study: effects of fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers.
- L. Dragsted, A. Pedersen, +12 authors B. Sandström
- Chemistry, MedicineThe American journal of clinical nutrition
- 1 June 2004
Fruit and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the vitamins and minerals that fruit and vegetables are known to contain.
Green tea extract only affects markers of oxidative status postprandially: lasting antioxidant effect of flavonoid-free diet*
- J. Young, L. Dragstedt, +10 authors B. Sandström
- Biology, MedicineBritish Journal of Nutrition
- 1 April 2002
The overall effect of the 10-week period without dietary fruits and vegetables was a decrease in oxidative damage to DNA, blood proteins, and plasma lipids, concomitantly with marked changes in antioxidative defence.
Macrophage Activation Downregulates the Degradative Capacity of the Phagosome
Functional alterations in the lumenal environment of the maturing phagosome following stimulation of macrophages with interferon‐γ and/or lipopolysaccharide are characterized to be consistent with limiting proteolysis in the early phagosomes to maximize epitope generation and antigen presentation while sequestering the degradative capacity in the late phagolysosome.
Lipid topology and physical properties of the outer mitochondrial membrane of the yeast, Saccharomyces cerevisiae.
- C. Sperka-Gottlieb, A. Hermetter, F. Paltauf, G. Daum
- Biology, MedicineBiochimica et biophysica acta
- 22 December 1988
The data presented here show, that the outer mitochondrial membrane, in spite of its close contact to the inner membrane, is distinct not only with respect to its protein pattern, but also withrespect to its lipid composition and physical membrane properties.
Seeds and oil of the Styrian oil pumpkin : Components and biological activities
The production and economic value of this edible oil as well as its composition on a molecular basis, including fatty acids, vitamins, phytosterols, minerals, polyphenols, and the compounds responsible for its pigments, taste and flavor are described.
Screening for Hydrolytic Enzymes Reveals Ayr1p as a Novel Triacylglycerol Lipase in Saccharomyces cerevisiae*
- B. Ploier, M. Scharwey, +6 authors G. Daum
- Biology, MedicineThe Journal of Biological Chemistry
- 1 November 2013
The identification of Ayr1p was identified as a novel triacylglycerol lipase of yeast lipid droplets and confirmed the hydrolytic potential of the peroxisomal Lpx1p in vivo, opening the view for a broader network of lipolytic enzymes in yeast.
Enhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein (*)
- C. Blencowe, A. Hermetter, G. Kostner, H. Deigner
- Chemistry, MedicineThe Journal of Biological Chemistry
- 29 December 1995
The results suggest that PAF acetylhydrolase exhibits an enhanced association with Lp (a) due to an increased affinity to Lp(a) apolipoprotein B.