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Driving simulator sickness: Impact on driving performance, influence of blood alcohol concentration, and effect of repeated simulator exposures.
- A. Helland, S. Lydersen, L. Lervag, G. Jenssen, J. Mørland, L. Slørdal
- Accident; analysis and prevention
- 1 September 2016
Simulator sickness is a major obstacle to the use of driving simulators for research, training and driver assessment purposes. The purpose of the present study was to investigate the possible… Expand
Comparison of driving simulator performance with real driving after alcohol intake: a randomised, single blind, placebo-controlled, cross-over trial.
The purpose of this study was to establish and validate a driving simulator method for assessing drug effects on driving. To achieve this, we used ethanol as a positive control, and examined whether… Expand
Ethanol and drug findings in women consulting a Sexual Assault Center--associations with clinical characteristics and suspicions of drug-facilitated sexual assault.
- C. Hagemann, A. Helland, Olav Spigset, Ketil Arne Espnes, K. Ormstad, B. Schei
- Journal of forensic and legal medicine
- 1 August 2013
The purpose of the study was to describe toxicological findings among women seeking health care after sexual assault, and to assess the relationship with so-called proactive DFSA (drug facilitated… Expand
Post-mortem levels and tissue distribution of codeine, codeine-6-glucuronide, norcodeine, morphine and morphine glucuronides in a series of codeine-related deaths.
- J. Frost, Trine N Løkken, A. Helland, I. Nordrum, L. Slørdal
- Forensic science international
- 1 May 2016
This article presents levels and tissue distribution of codeine, codeine-6-glucuronide (C6G), norcodeine, morphine and the morphine metabolites morphine-3-glucuronide (M3G) and morphine-6-glucuronide… Expand
Two Hospitalizations and One Death After Exposure to Ortho-Fluorofentanyl.
Two young males were hospitalized with miosis and respiratory dysfunction after exposure to a white powder obtained from a foreign source by mail. A few days later, one of the males was found dead at… Expand
Quantification of 21 antihypertensive drugs in serum using UHPLC-MS/MS.
- P. O. M. Gundersen, A. Helland, O. Spigset, S. Hegstad
- Chemistry, Medicine
- Journal of chromatography. B, Analytical…
- 1 July 2018
BACKGROUND Poor drug adherence in hypertensive patients can lead to treatment failure and increased cardiovascular morbidity, as well as increased costs to society. An analytical method based on… Expand
Prolonged elimination of paliperidone after administration of paliperidone palmitate depot injections.
- A. Helland, V. E. G. Syrstad, O. Spigset
- Journal of clinical psychopharmacology
- 1 February 2015
To the Editors: Paliperidone (9-hydroxy-risperidone), which is the pharmacologically active main metabolite of risperidone, has recently been approved for use as an antipsychotic agent on its own,… Expand
Evaluation of measures of impairment in real and simulated driving: Results from a randomized, placebo-controlled study
ABSTRACT Objective: Standard deviation of lateral position (SDLP) is often the primary outcome in experimental studies on impaired driving. However, other measures may be easier and more practical to… Expand
Serum Concentrations of Paliperidone After Administration of the Long-Acting Injectable Formulation
Background: The pharmacokinetics of long-acting intramuscular paliperidone in a naturalistic setting is not well documented. The objective of this study was to investigate the relationship between… Expand