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An organ culture of postnatal rat liver slices
A technique for the organ culture of postnatal and adult rat liver has been developed and orotate was shown to be spread over the entire slice of neonatal liver, and induction of urea cycle enzymes by cortisol was demonstrated in cultures of liver from adrenalectomized adult animals. Expand
Hormonal regulation of four urea cycle enzymes in postnatal rat liver in organ culture.
The administration of hydrocortisone to 3- to 15-day-old rats increased the levels of hepatic argininosuccinate synthetase (ASS) and arginase and amplified the response of ASS to dibutyryl cyclic AMP. Expand