A. Harper

Publications423
h-index50
Citations12,605
Highly Influential Citations224
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Branched-chain amino acid metabolism.
TLDR
Rates of Metab olism of BCAA and BCKA and Interorgan C ooperativity in the MetabOlism of BCA A Nitrogen.
Dietary guidelines for Americans.
  • A. Harper
  • Medicine
    The American journal of clinical nutrition
  • 1981
TLDR
Since the guidelines were first issued back in 1980, Americans have gotten slightly healthier, except for children, got significantly bigger, gotten significantly bigger (especially children), and gotten very, very confused about what they should be eating.
Effects of ingestion of disproportionate amounts of amino acids.
Enhanced immune responses in broiler chicks fed methionine-supplemented diets.
TLDR
It is suggested that methionine is required for select components of the antibody response, which effect might be related to T-cell help.
Amino acid diets and maximal growth in the rat.
TLDR
From the late 1940's until the present there has been considerable controversy over the question of whether there is a specific compound in protein which in creases the growth rate of animals fed an amino acid diet and an examination of the literature indicates that maximal growth rate has, in fact, never been ob tained routinely.
Metabolic adaptations in higher animals. V. The study of metabolic pathways by means of metabolic adaptations.
Food intake regulation: amino acid toxicity and changes in rat brain and plasma amino acids.
Sulfur amino acid and methyl donor status of corn-soy diets fed to starting broiler chicks and turkey poults.
TLDR
It is concluded that (within the limits of the experimental model) corn-soy type diets contain an adequate amount of total sulfur amino acid for chicks, but not poults, when sufficient choline or betaine are provided.
Amino Acid Toxicities and Imbalances
TLDR
This chapter discusses amino-acid toxicities and imbalances, a change in the proportions of amino acids in a diet that results in a depression in food intake or growth rate that can be completely prevented by a supplement of the indispensable amino acid present in least amount in the diet in relation to the amount required for optimal performance.
Adaptation of rats to diets containing different levels of protein: effects on food intake, plasma and brain amino acid concentrations and brain neurotransmitter metabolism.
TLDR
The results indicate that protein intake appeared to be related to the animal's ability to maintain brain total IAA content between some upper and lower limits, and was accomplished initially through downward adjustment of protein intake and subsequently through an increase in catabolic capacity for the amino acids.
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