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Epidemiology of laboratory-associated infections.
This chapter examines the extent of documented laboratory-associated infections (LAIs) classified as viral, parasitic, bacterial, fungal, including rickettsial infection by reviewing those reported
Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae, type b.
TLDR
Rises in serum bactericidal activity against H. influenzae type b generally accompanied rises in antibody concentration as measured by the antigen-binding assay, which was not related to the preimmunization antibody concentration.
Phenotypic and genetic variation in the susceptibility of Haemophilus influenzae type b to antibodies to somatic antigens.
TLDR
It is reported that a similar phenotypic shift occurs when strain Eag is incubated with dialysate of human serum, that the increased resistance is to antibodies against determinants in the lipopolysaccharide not for the somatic antigens generally, and that most strains of H.i.b undergo the shift.
In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol
TLDR
It is concluded that fluorinated analogs of chloramphenicol and thiAMPhenicol have considerable in vitro activity against a broad spectrum of chlorampshenicol-thiampenicol-resistant, gram-negative bacteria.
Evaluation of a Rapid β-Lactamase Test for Detecting Ampicillin-Resistant Strains of Hemophilus influenzae Type b
TLDR
Rapid β-lactamase assay is a reliable detector of ampicillin resistance in H. influenzae type b and would facilitate early discontinuation of chloramphenicol therapy in patients infected with amicillin-sensitive bacteria.
Evaluation of a rapid beta-lactamase test for detecting ampicillin-resistant strains of Hemophilus influenzae type b.
TLDR
Rapid beta-lactamase assay assay is a reliable detector of ampicillin resistance in H. influenzae type b and would facilitate early discontinuation of chloramphenicol therapy in patients infected withAmpicillin-sensitive bacteria.
R-factor transfer in selenite and tetrathionate broths.
TLDR
After overnight incubation of R(+)Escherichia coli with R(-)Salmonella typhimurium in selenite and tetrathionate with Brilliant Green broths, R-factor transfer was demonstrated in 10 of 12 experiments, suggesting transfer of R factors in commonly used enrichment broths may give rise to falsely resistant antibiotic patterns in Salmonella.
Laboratory-Associated Infections
TLDR
The review of actual case studies illustrates the importance of adhering to biosafety protocols and may trigger changes in laboratory procedures.
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