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Initiation and Use of Propranolol for Infantile Hemangioma: Report of a Consensus Conference
TLDR
The multidisciplinary team agreed on a number of recommendations that arose from a review of existing evidence, including when to treat complicated IH; contraindications and pretreatment evaluation protocols; propranolol use in PHACE syndrome; formulation, target dose, and frequency of proPRanolol; initiation of propr ethanol in infants; cardiovascular monitoring; ongoing monitoring; and prevention of hypoglycemia. Expand
Prospective Study of Infantile Hemangiomas: Clinical Characteristics Predicting Complications and Treatment
TLDR
Large size, facial location, and/or segmental morphology are the most important predictors of poor short-term outcomes as measured by complication and treatment rates in infantile hemangiomas. Expand
Consensus Statement on Diagnostic Criteria for PHACE Syndrome
TLDR
A multidisciplinary group of specialists with expertise in PHACE syndrome drafted initial diagnostic criteria on the basis of review of published, peer-reviewed medical literature and clinical experience and used a consensus method. Expand
A prospective study of PHACE syndrome in infantile hemangiomas: Demographic features, clinical findings, and complications
TLDR
Correlation to the anatomic location of the hemangioma appears to be helpful in determining which structural abnormalities might be present in this syndrome, and whether certain demographic, prenatal or perinatal risk factors predispose infants to this syndrome. Expand
Infantile Hemangiomas: Current Knowledge, Future Directions. Proceedings of a Research Workshop on Infantile Hemangiomas
TLDR
Ilona J. Frieden, M.D, Ph.D.,* Anita N. Haggstrom, M,D.,§ Eulalia Baselga, MD.,†† Maria C. Garzon,M.D. Expand
Growth Characteristics of Infantile Hemangiomas: Implications for Management
TLDR
Most infantile hemangioma growth occurs before 5 months, yet 5 months was also the mean age at first visit to a specialist, and recognition of growth characteristics and factors that predict the need for follow-up could help aid in clinical decision-making. Expand
Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics.
TLDR
Infants with hemangiomas are more likely to be female, white non-Hispanic, premature, and products of multiple gestations, and perinatal associations include older maternal age, placenta previa, and pre-eclampsia. Expand
Patterns of Infantile Hemangiomas: New Clues to Hemangioma Pathogenesis and Embryonic Facial Development
TLDR
The observed patterns resemble previously described facial developmental units on the lower face but are distinctly different on the upper face, suggest that neural crest derivatives may play a role in the development of facial hemangiomas, and help standardize the nomenclature of facial segmental hemangIoma risks and behavior. Expand
PHACE Syndrome: Current Knowledge, Future Directions
TLDR
This article represents a summary of the discussions held at the first‐ever workshop on PHACE syndrome, an important and recently described neurocutaneous syndrome, attended by a broad range of medical specialists. Expand
Risk for PHACE Syndrome in Infants With Large Facial Hemangiomas
TLDR
In infants with large facial hemangiomas, one-third have extracutaneous manifestations consistent with the diagnosis of PHACE syndrome, most commonly cerebrovascular and cardiovascular anomalies. Expand
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