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- Publications
- Influence
Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease
- H. Ishiura, S. Shibata, +47 authors S. Tsuji
- Biology, Medicine
- Nature Genetics
- 22 July 2019
Noncoding repeat expansions cause various neuromuscular diseases, including myotonic dystrophies, fragile X tremor/ataxia syndrome, some spinocerebellar ataxias, amyotrophic lateral sclerosis and… Expand
Small intestinal bacterial overgrowth in Parkinson's disease.
- A. H. Tan, S. Mahadeva, +11 authors S. Lim
- Medicine
- Parkinsonism & related disorders
- 1 May 2014
BACKGROUND
Recent studies reported a high prevalence of small intestinal bacterial overgrowth (SIBO) in Parkinson's disease (PD), and a possible association with gastrointestinal symptoms and worse… Expand
Helicobacter pylori infection is associated with worse severity of Parkinson's disease.
- A. H. Tan, S. Mahadeva, +14 authors S. Lim
- Medicine
- Parkinsonism & related disorders
- 1 March 2015
BACKGROUND
Some studies have suggested that chronic Helicobacter pylori (HP) infection can aggravate the neurodegenerative process in Parkinson's disease (PD), and targeted intervention could… Expand
Augmentation of Autoantibodies by Helicobacter pylori in Parkinson’s Disease Patients May Be Linked to Greater Severity
- Gunasekaran Suwarnalata, A. H. Tan, +6 authors J. Vadivelu
- Medicine
- PloS one
- 21 April 2016
Parkinson's disease (PD) is the second most common chronic and progressive neurodegenerative disorder. Its etiology remains elusive and at present only symptomatic treatments exists. Helicobacter… Expand
Altered body composition, sarcopenia, frailty, and their clinico-biological correlates, in Parkinson's disease.
INTRODUCTION
Low body weight in Parkinson's disease (PD) is poorly understood despite the associated risks of malnutrition, fractures, and death. Sarcopenia (loss of muscle bulk and strength) and… Expand
Genome-wide association study of Parkinson’s disease in East Asians
Genome-wide association studies (GWAS) on Parkinson's disease (PD) have mostly been done in Europeans and Japanese. No study has been done in Han Chinese, which make up nearly a fifth of the world… Expand
Parkinson’s disease and the gastrointestinal microbiome
- M. Lubomski, A. H. Tan, S. Lim, A. Holmes, R. Davis, C. Sue
- Medicine
- Journal of Neurology
- 30 April 2019
Recently, there has been a surge in awareness of the gastrointestinal microbiome (GM) and its role in health and disease. Of particular note is an association between the GM and Parkinson’s disease… Expand
Parkinson's disease in the Western Pacific Region
- Shen-Yang Lim, A. H. Tan, A. Ahmad-Annuar, C. Klein, A. Lang
- Medicine
- The Lancet Neurology
- 1 September 2019
1·8 billion people of diverse ethnicities and cultures live in the Western Pacific Region. The increasing longevity of populations in this region is a major contributor to the exponential increase in… Expand
Knowledge of Parkinson's Disease in a Multiethnic Urban Asian Setting.
BACKGROUND
Public knowledge regarding Parkinson's disease (PD) is important to facilitate good health-seeking behavior, but the literature on this topic is scarce.
OBJECTIVE
We aimed to explore the… Expand