A. Guthrie

Publications157
h-index32
Citations3,015
Highly Influential Citations195
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Re-emergence of bluetongue, African horse sickness, and other Orbivirus diseases
TLDR
Although climate change has been incriminated in the emergence of BTV infection of ungulates, the precise role of anthropogenic factors and the like is less certain and it is not yet clear what the future holds in terms of these diseases, nor of other potentially important but poorly characterized Orbiviruses.
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Sequence heterogeneity in the 18S rRNA gene within Theileria equi and Babesia caballi from horses in South Africa.
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Experimental Reproduction of Severe Bluetongue in Sheep
TLDR
A reliable model for experimental reproduction of fulminant BT in sheep will facilitate future studies to better characterize the pathogenesis of this disease, particularly as it regards the mechanisms responsible for the increased vascular permeability that characterizes BT and related orbiviral diseases such as African horse sickness.
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Development and evaluation of real-time PCR assays for the quantitative detection of Babesia caballi and Theileria equi infections in horses from South Africa.
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An epizoological study of wastage in thoroughbred racehorses in Gauteng, South Africa.
TLDR
It was concluded that lameness and respiratory disorders were the major causes of wastage in Thoroughbred racehorses in Gauteng.
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Variation in the NS3 gene and protein in South African isolates of bluetongue and equine encephalosis viruses.
TLDR
The South African BTV NS3 genes were found to have the highestlevel of sequence variation for BTV, while the highest level of protein variation of BTVNS3 was found between South African and Asian BTV isolates.
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Helminth levels of working donkeys kept under different management systems in the Moretele 1 district of the North-West Province, South Africa.
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The circumstances surrounding the outbreak and spread of equine influenza in South Africa.
TLDR
The release of in-contact horses from quarantine three days after the arrival of these six horses played a role in the rapid spread of the disease in South Africa, and other outbreaks of disease were associated with viral introduction by personnel or contaminated instruments.
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The classification of seven serotypes of equine encephalosis virus and the prevalence of homologous antibody in horses in South Africa.
TLDR
The identification of donors with antibody resulting from infection with multiple serotypes indicated a low level of cross-protection in horses to natural reinfection, confirming the independent persistence of the viruses in a maintenance cycle.
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Sequence heterogeneity in the gene encoding the rhoptry-associated protein-1 (RAP-1) of Babesia caballi isolates from South Africa.
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