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Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification.
Islet beta-cells express receptors for low density (LDL) and very low density (VLDL) lipoproteins that are internalized by receptor-mediated endocytosis. The present study examined whether thisExpand
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Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age.
Studies with I(125)-labeled low-density lipoproteins (LDLs) have shown the presence of high-affinity LDL receptors on insulin-producing beta cells but not on neighboring alpha cells. By usingExpand
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Low Density Lipoprotein Binding and Uptake by Human and Rat Islet b Cells
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic b cells. This studyExpand
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Low Density Lipoprotein Binding and Uptake by Human and Rat Isletβ Cells.
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic beta cells. This studyExpand
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Low density lipoprotein binding and uptake by human and rat islet beta cells.
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic beta cells. This studyExpand
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Comparative study of the orientation of the dipole change vector for the isolated C-H stretch in partially deuterated alkyl halides
Abstract The vapour phase infrared contour of the isolated CH stretch fundamental, obtained at 0.5 cm −1 resolution, has been simulated in several partially deuterated alkyl halides, as well as inExpand
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The dipole change vector for isolated CH stretches 1. Partially deuterated methyl bromide
Abstract The vapour phase infrared contour of the isolated CH stretch fundamental of CHD 2 Br, obtained at 0.5 cm −1 resolution, has been simulated using anharmonic rigid asymmetric topExpand
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The dipole gradient for isolated CC stretches 2. Partially deuterated methyl fluoride, methyl chloride and methyl iodide
Abstract The vapour phase infrared contours, at 0.5 cm −1 resolution, of the CC stretch fundamental in CHD 2 F, CHD 2 Cl and CHD 2 I have simulated using anharmonic rigid asymmetric topExpand
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