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- Publications
- Influence
Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification.
- M. Cnop, J. C. Hannaert, A. Grupping, D. Pipeleers
- Medicine, Chemistry
- Endocrinology
- 1 September 2002
Islet beta-cells express receptors for low density (LDL) and very low density (VLDL) lipoproteins that are internalized by receptor-mediated endocytosis. The present study examined whether this… Expand
Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age.
- M. Cnop, A. Grupping, A. Hoorens, L. Bouwens, M. Pipeleers-Marichal, D. Pipeleers
- Biology, Medicine
- The American journal of pathology
- 2000
Studies with I(125)-labeled low-density lipoproteins (LDLs) have shown the presence of high-affinity LDL receptors on insulin-producing beta cells but not on neighboring alpha cells. By using… Expand
Low Density Lipoprotein Binding and Uptake by Human and Rat Islet b Cells
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic b cells. This study… Expand
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Low Density Lipoprotein Binding and Uptake by Human and Rat Isletβ Cells.
- A. Grupping, M. Cnop, C. V. van Schravendijk, J. C. Hannaert, T. V. van Berkel, D. Pipeleers
- Chemistry, Medicine
- Endocrinology
- 1 October 1997
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic beta cells. This study… Expand
Low density lipoprotein binding and uptake by human and rat islet beta cells.
- A. Grupping, M. Cnop, C. V. van Schravendijk, J. C. Hannaert, T. V. van Berkel, D. Pipeleers
- Medicine
- Endocrinology
- 1997
Abnormalities in lipoprotein metabolism are common in diabetes. It is unknown whether variations in form or concentration of lipoproteins influence the function of pancreatic beta cells. This study… Expand
The Dipole Gradient for Isolated C-H Stretches. Part 2. Partially Deuterated Methyl Fluoride, Methyl Chloride and Methyl Iodide.
- A. Grupping, D. C. Mckean, B. Veken
- Chemistry
- 1 March 1994
Comparative study of the orientation of the dipole change vector for the isolated C-H stretch in partially deuterated alkyl halides
- A. Grupping, D. C. Mckean, B. Veken
- Chemistry
- 1 March 1993
Abstract The vapour phase infrared contour of the isolated CH stretch fundamental, obtained at 0.5 cm −1 resolution, has been simulated in several partially deuterated alkyl halides, as well as in… Expand
The dipole change vector for isolated CH stretches 1. Partially deuterated methyl bromide
- A. Grupping, D. C. Mckean, B. Veken
- Chemistry
- 25 May 1993
Abstract The vapour phase infrared contour of the isolated CH stretch fundamental of CHD 2 Br, obtained at 0.5 cm −1 resolution, has been simulated using anharmonic rigid asymmetric top… Expand
The dipole gradient for isolated CC stretches 2. Partially deuterated methyl fluoride, methyl chloride and methyl iodide
- A. Grupping, D. C. Mckean, B. Veken
- Chemistry
- 3 December 1993
Abstract The vapour phase infrared contours, at 0.5 cm −1 resolution, of the CC stretch fundamental in CHD 2 F, CHD 2 Cl and CHD 2 I have simulated using anharmonic rigid asymmetric top… Expand