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The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.
TLDR
The data suggest that ghrelin might have widespread physiological effects via different, partly unidentified, subtypes of the GHS-R in endocrine and non-endocrine tissues.
Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline.
TLDR
The practice of hypoglycemia risk factor reduction is recommended--addressing the issue of hypglycemia, applying the principles of intensive glycemic therapy, and considering both the conventional risk factors and those indicative of compromised defenses against falling plasma glucose concentrations--in persons with diabetes.
The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states.
TLDR
A differential diagnosis of ACTH-Dependent Cushing’s Syndrome and differentiation from Pseudo-Cushing”s States are presented.
The diagnosis and medical management of advanced neuroendocrine tumors.
TLDR
Assessment of specific or general tumor markers offers high sensitivity in establishing the diagnosis and can also have prognostic significance, and therapy with radionuclides may be used for tumors exhibiting uptake to a diagnostic scan, either after surgery to eradicate microscopic residual disease or later if conventional treatment or biotherapy fails.
Diagnosis and complications of Cushing's syndrome: a consensus statement.
TLDR
The consensus statement on diagnostic criteria and the diagnosis and treatment of complications of this syndrome reached at the workshop is hereby summarized.
ENETS Consensus Guidelines for the Management of Patients with Neuroendocrine Neoplasms from the Jejuno-Ileum and the Appendix Including Goblet Cell Carcinomas
TLDR
This poster presents a poster presented at the 2016 European Congress of Medical Oncology and Hepatology/Gastroenterology/Oncology Congress in Vienna, Austria, presenting the findings of a two-week clinical trial of positron emission tomography/computed Tomography/answers for the diagnosis of central giant cell granuloma.
Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase*
TLDR
It is demonstrated that AMPK not only links the orexigenic effects of endocannabinoids and ghrelin in the hypothalamus but also their effects on the metabolism of peripheral tissues, which provides a mechanism for a number of their known actions, including the reduction in infarct size in the myocardium, an increase in adipose tissue, and stimulation of appetite.
The ectopic adrenocorticotropin syndrome: clinical features, diagnosis, management, and long-term follow-up.
TLDR
A variety of tests and imaging studies are necessary for the correct diagnosis of the EAS, but up to 20% of cases present a covert or occult EAS syndrome, and these cases require a prolonged follow-up, review, and repetition of diagnostic tests and scans.
Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours
TLDR
All patients should be evaluated for second endocrine tumours and possibly for other gut cancers (grade C) and all patients with sporadic or familial bronchial or gastric carcinoid should have a family history evaluation and consideration of testing for germline MEN1 mutations.
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