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Blood flow increases linearly in rat somatosensory cortex with increased whisker movement frequency
TLDR
These data demonstrate linear blood flow responses to presumptive linear increases in neuronal activity with sufficient vascular reserve capacity to overcome moderate CO2-induced dilation, and support the use of blood flow changes in neuroimaging studies. Expand
Suppression of angiotensin-converting enzyme expression and activity by shear stress.
TLDR
Elevations in the level of shear stress alter endothelial cell function by suppressing ACE gene and protein expression in vitro and in vivo, and suggest that Restriction of vessel diameter increased blood flow velocity and caused reduction in vascular ACE activity in vivo. Expand
Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies.
TLDR
This study provides investigators with baseline information for both kidney and liver with respect to 'normal' changes in gene expression influenced by time of day and feeding state and identifies 18 new genes that should be investigated for a role in circadian rhythms in peripheral tissues. Expand
Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays
TLDR
Microarrays of UV cross-linked unmodified oligonucleotides provided sensitive and specific measurements for most of the genes studied, and in each case the cDNA results were more accurate, as determined by real-time PCR. Expand
MR‐derived cerebral blood volume maps: Issues regarding histological validation and assessment of tumor angiogenesis
TLDR
The results demonstrate that while fractional area (FA) does not provide a good measure of CBV, FA corrected for section thickness effects does, and a new independent correlative measure should enable efficient and accurate progress in the development of MRI methods to evaluate tumor angiogenesis. Expand
Carotid Sinus Baroreceptor Reflex Control of Respiration
TLDR
It is indicated that not only does the carotid sinus baroreceptor reflex control arterial pressure, but it also simultaneously influences ventilation, through changes in both respiratory frequency and tidal volume. Expand
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.
TLDR
It is suggested that acute and chronic elevations in circulating ANG II levels increase the formation of 20- HETE in the kidney and peripheral vasculature and that 20-HETE contributes to the acute and Chronic pressor effects of ANG II. Expand
Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training.
TLDR
The results confirm the role of angiotensin II and VEGF in angiogenesis induced by exercise. Expand
Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats.
TLDR
The development of a female rat systems biology map of cardiovascular function represents the first attempt to prioritize those regions of the genome important for development of hypertension and end organ damage in female rats. Expand
Microvascular rarefaction and tissue vascular resistance in hypertension.
TLDR
It is demonstrated that vessel rarefaction significantly influences tissue blood flow resistance to a degree comparable with vessel constriction; however, unlike constriction, microvascular rarefactions markedly altered blood flow distribution in the authors' model of the hamster cheek pouch vascular bed. Expand
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