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Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource-Constrained Settings: Individual Participant Data Meta-analysis of Observational Studies
Haileyesus Getahun and colleagues report the development of a simple, standardized tuberculosis (TB) screening rule for resource-constrained settings, to identify people living with HIV who needExpand
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"That is why I stopped the ART": Patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme
BackgroundAs ART programmes in African settings expand beyond the pilot stages, adherence to treatment may become an increasing challenge. This qualitative study examines potential barriers to, andExpand
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Use of traditional medicine by HIV-infected individuals in South Africa in the era of antiretroviral therapy
Abstract As antiretroviral therapy (ART) becomes more available in African countries, the potential for interaction with traditional medicines becomes more important. We carried out a cross-sectionalExpand
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Morbidity and mortality in South African gold miners: impact of untreated disease due to human immunodeficiency virus.
A cohort of 1792 human immunodeficiency virus (HIV)-positive and 2970 HIV-negative South African miners was observed for 12 months starting in February 1998. All-cause hospitalizations and deathsExpand
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Hepatitis B virus infection and response to antiretroviral therapy (ART) in a South African ART program.
BACKGROUND Coinfection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is common in Africa; however, the impact of HBV infection on the outcomes of antiretroviral therapy programsExpand
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Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control.
BACKGROUND Although failure of tuberculosis (TB) control in sub-Saharan Africa is attributed to the HIV epidemic, it is unclear why the directly observed therapy short-course (DOTS) strategy isExpand
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Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis B
Objective:Hepatotoxicity is a significant complication of antiretroviral therapy (ART). We assessed the incidence of and risk factors for hepatotoxicity among HIV-infected individuals on ART in SouthExpand
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Early predictors of mortality from Pneumocystis jirovecii pneumonia in HIV-infected patients: 1985-2006.
BACKGROUND Pneumocystis jirovecii pneumonia (PCP) remains the leading cause of opportunistic infection among human immunodeficiency virus (HIV)-infected persons. Previous studies of PCP thatExpand
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Liquid vs. solid culture for tuberculosis: performance and cost in a resource-constrained setting.
SETTING National Health Laboratory Services tuberculosis (TB) laboratory, South Africa. OBJECTIVES To compare Mycobacterium Growth Indicator Tube (MGIT) with Löwenstein-Jensen (LJ) medium withExpand
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The natural history of HIV-1 and HIV-2 infections in adults in Africa: a literature review.
About 30 million people in Africa are estimated to be living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), yet data about the natural history of infection on theExpand
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