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The neural crest
  • A. Graham
  • Medicine, Biology
  • Current Biology
  • 13 May 2003
It is generally accepted that the vertebrates evolved from protochordates ancestors, probably from an animal akin to modern day Amphioxus, a sessile filter feeder whose anatomical organisation is inExpand
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The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest
THE pattern of skeletal structures and muscles in the branchial region of the head is profoundly influenced by the neural crest1, whose cells arise at discrete segmental levels of the chickExpand
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Induction of the epibranchial placodes.
The cranial sensory ganglia, in contrast to those of the trunk, have a dual embryonic origin arising from both neurogenic placodes and neural crest. Neurogenic placodes are focal thickenings ofExpand
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Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes.
Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long beenExpand
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Integration Between the Epibranchial Placodes and the Hindbrain
Developmental integration results from coordination among components of different embryonic fields to realize the later anatomical and functional relationships. We demonstrate that in the chick head,Expand
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Early Steps in the Production of Sensory Neurons by the Neurogenic Placodes
Neurogenic placodes are specialized regions of the embryonic ectoderm that generate the majority of the neurons of the cranial sensory ganglia. Here we have accurately determined the onset ofExpand
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The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation
Endocannabinoids are retrograde neurotransmitters, which act upon the presynaptically located, G-protein coupled receptor CB1, to modulate synaptic transmission in the adult brain. Recently, however,Expand
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Trunk Neural Crest Has Skeletogenic Potential
During early vertebrate development, neural crest cells emerge from the dorsal neural tube, migrate into the periphery, and form a wide range of derivatives. There is, however, a significantExpand
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Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions.
Collapsin-1 belongs to the Semaphorin family of molecules, several members of which have been implicated in the co-ordination of axon growth and guidance. Collapsin-1 can function as a selectiveExpand
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Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain.
Neural crest cells originate at three discontinuous levels along the rostrocaudal axis of the chick rhombencephalon, centred on rhombomeres 1 and 2, 4 and 6, respectively. These are separated by theExpand
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