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The Hippocampal-VTA Loop: Controlling the Entry of Information into Long-Term Memory
The control of firing pattern in nigral dopamine neurons: burst firing
The data suggest that the increased calcium influx accompanying an increased firing rate triggers burst firing, possibly by inactivating a potassium conductance.
Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission
- S. Floresco, A. West, B. Ash, H. Moore, A. Grace
- Biology, PsychologyNature Neuroscience
- 1 September 2003
Dissociable regulation of dopamine neuron discharge by two separate afferent systems in rats is reported; inhibition of pallidal afferents selectively increased the population activity of dopamine neurons, whereas activation of pedunculopontine inputs increased burst firing.
Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
- A. Grace
- Psychology, BiologyNeuroscience
- 31 December 1991
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization
The control of firing pattern in nigral dopamine neurons: single spike firing
In vivo intracellular injection of the calcium chelator EGTA will cause DA cells to fire in a regular, pacemaker pattern, with the amplitude of the afterhyperpolarization being proportional to the number of spikes in a train.
Cortico-Basal Ganglia Reward Network: Microcircuitry
A fuller appreciation of the circuitry interconnecting the nucleus accumbens and ventral tegmental area should serve to advance discovery of new treatment options for drugs of abuse or psychiatric disorders.
Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia