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The control of firing pattern in nigral dopamine neurons: burst firing
  • A. Grace, B. Bunney
  • Biology
    The Journal of neuroscience : the official…
  • 1 November 1984
TLDR
The data suggest that the increased calcium influx accompanying an increased firing rate triggers burst firing, possibly by inactivating a potassium conductance.
Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission
TLDR
Dissociable regulation of dopamine neuron discharge by two separate afferent systems in rats is reported; inhibition of pallidal afferents selectively increased the population activity of dopamine neurons, whereas activation of pedunculopontine inputs increased burst firing.
The control of firing pattern in nigral dopamine neurons: single spike firing
  • A. Grace, B. Bunney
  • Biology
    The Journal of neuroscience : the official…
  • 1 November 1984
TLDR
In vivo intracellular injection of the calcium chelator EGTA will cause DA cells to fire in a regular, pacemaker pattern, with the amplitude of the afterhyperpolarization being proportional to the number of spikes in a train.
Cortico-Basal Ganglia Reward Network: Microcircuitry
TLDR
A fuller appreciation of the circuitry interconnecting the nucleus accumbens and ventral tegmental area should serve to advance discovery of new treatment options for drugs of abuse or psychiatric disorders.
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