Garlic: a review of potential therapeutic effects
Throughout history, many different cultures have recognized the potential use of garlic for prevention and treatment of different diseases, but the exact mechanism of all ingredients and their long-term effects are not fully understood.
Spreading depression: a review of the clinical relevance
- A. Gorji
- Psychology, MedicineBrain Research Reviews
- 1 December 2001
Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex
Spreading depolarization of cells in cerebral grey matter is characterized by massive ion translocation, neuronal swelling and large changes in direct current-coupled voltage recording. The…
Comparison of Brain Extracellular Fluid, Brain Tissue, Cerebrospinal Fluid, and Serum Concentrations of Antiepileptic Drugs Measured Intraoperatively in Patients with Intractable Epilepsy
Concentrations of AEDs in the extracellular space of human neocortical tissue were measured by using intraoperative microdialysis (IOMD) in those parts of the brain that had to be removed for therapeutic reasons.
Effect of Cannabinoid Receptor Activation on Spreading Depression
- H. Kazemi, M. Rahgozar, E. Speckmann, A. Gorji
- Biology, MedicineIranian Journal of Basic Medical Sciences
- 1 July 2012
Suppression of CSD by activation of CB1 receptors points to the potential therapeutic effects of cannabinoids in migraine with aura.
Lavender and the Nervous System
- Peir Hossein Koulivand, Maryam Khaleghi Ghadiri, A. Gorji
- PsychologyEvidence-Based Complementary and Alternative…
- 14 March 2013
A survey on current experimental and clinical state of knowledge about the effect of lavender on the nervous system is given.
Spreading depression in human neocortical slices
Spreading Depression Enhances Human Neocortical Excitability in vitro
Investigation of the effects of CSD on the field excitatory postsynaptic potentials (fEPSP) and the induction of long-term potentiation (LTP) in human neocortical slices obtained during epilepsy surgery indicates that CSD facilitates synaptic excitability and efficacy in human neoconsortical tissues.
Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?
Effect of Levetiracetam on Epileptiform Discharges in Human Neocortical Slices
Summary: Purpose: The anticonvulsant effects of the novel antiepileptic drug (AED) levetiracetam (LEV) were tested in neocortical slice preparations from 23 patients who underwent surgery for the…