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Monitoring levels of preservative sensitivity in Europe
The current high level of sensitivity to MDBGN requires an urgent safety re‐evaluation and risk assessment update along with consideration of immediate lowering of use concentrations, especially in leave‐on products.
Thoughts on sensitizers in a standard patch test series
- M. Bruze, L. Condé‐Salazar, A. Goossens, L. Kanerva, I. White
- MedicineContact dermatitis
- 1 November 1999
The requirements to be fullled by a Sensitizer in a standard patch test series are discussed in this article and a procedure of investigations is proposed before a sensitizer is included in astandard series.
Hand eczema severity and quality of life: a cross‐sectional, multicentre study of hand eczema patients
In this study, QoL in hand eczema patients is assessed and related to age, sex, severity, and diagnostic subgroups.
Monitoring the European standard series in 10 centres 1996–2000
A 5‐year retrospective study of the frequency of sensitization to the 25 allergens of the European standard series was conducted in 10 centres in 8 European countries, and the results were useful for decisions on the future composition of the standard series.
Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe.
- M. Matura, A. Goossens, A. Karlberg
- MedicineJournal of the American Academy of Dermatology
- 1 November 2002
The high frequency of oxidized limonene allergy provides clinical evidence for the European classification of R-(+)-limonene that contains oxidation products as skin sensitizers.
Photopatch testing: recommendations for a European photopatch test baseline series
A list of photoallergens that should form part of a baseline series for photopatch testing in Europe is recommended, which contains mainly ultraviolet filters and drugs, mostly non‐steroidal anti‐inflammatory drugs.
Not only oxidized R‐(+)‐ but also S‐(−)‐limonene is a common cause of contact allergy in dermatitis patients in Europe
Clinical evidence for the importance of oxidation products of limonene in contact allergy is provided, it seems advisable to screen consecutive dermatitis patients with oxidizedLimonene 3% petrolatum, although this patch test material is not yet commercially available.
Selected oxidized fragrance terpenes are common contact allergens
This study aimed to determine the frequency and characteristics of allergic reactions to selected oxidized fragrance terpenes other than limonene, and found that 58% had fragrance‐related contact allergy and/or a positive history for adverse reaction to fragrances.
Whilst Rome Burns: The Epidemic of Contact Allergy to Methylisothiazolinone
In Europe a rise in contact allergy to MCI/MI, the only isothiazolinone patch tested in the baseline series, has been observed, and similar figures are being observed all over Europe, with alerts particularly during late 2012 in France and Belgium at the REVIDAL.
A European multicentre photopatch test study
Background The two most common agent groups currently responsible for photoallergic contact dermatitis (PACD) are organic ultraviolet (UV) absorbers in sunscreens and topical nonsteroidal…