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Deficit irrigation and rootstock: their effects on water relations, vegetative development, yield, fruit quality and mineral nutrition of Clemenules mandarin.
TLDR
Trees on 'Cleopatra' showed more efficient soil water extraction than trees on 'Carrizo', and maintained a higher plant water status, a higher gas exchange rate during periods of water stress and achieved faster recovery in gas exchange following irrigation after water stress. Expand
Quantification of endogenous neurotransmitters and related compounds by liquid chromatography coupled to tandem mass spectrometry.
TLDR
A straightforward liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 16 endogenous small polar compounds in rat plasma and brain homogenates and obtained a neuro-metabolic fingerprint of each drug that reflected their pharmacological profile. Expand
Evaluation of two glucuronides resistant to enzymatic hydrolysis as markers of testosterone oral administration
TLDR
The four markers presented seem to have an exceptional potential as biomarkers of T oral administration and were highlighted by their prolonged capacity to detect the T misuse in the case of one volunteer whose TG/EG barely exceeded his individual threshold. Expand
Determination of the steroid profile in alternative matrices by liquid chromatography tandem mass spectrometry
TLDR
A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of several steroids and their metabolites in amniotic fluid, saliva and breast milk is developed and validated. Expand
Evaluation of markers out of the steroid profile for the screening of testosterone misuse. Part I: Transdermal administration.
TLDR
Overall; this evaluation advises for the introduction of additional glucuronoconjugated markers in the screening of transdermal T administration. Expand
Determination of steroid profile in hair by liquid chromatography tandem mass spectrometry.
TLDR
A liquid chromatography-tandem mass spectrometry methodology for the determination of 11 steroids in hair, including 6 hormones and 5 metabolites revealed that with the exception of testosterone, beard is a suitable alternative to the hair determination of the steroid profile. Expand
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran
TLDR
Even if HHcy was observed in AIP patients receiving heme arginate, givosiran induced an aggravation of the dysregulation, causing a co‐increase of tHcy and methionine resembling classic homocystinuria. Expand
Improving liquid chromatography‐tandem mass spectrometry determination of polycarboxylic acids in human urine by chemical derivatization. Comparison of o‐benzyl hydroxylamine and 2‐picolyl amine
TLDR
Derivatization with oBHA showed important advantages against 2‐PA derivatization such as providing better sensitivity, more stable derivatives and allowing for the proper validation of a larger number of analytes. Expand
Comprehensive analysis of the tryptophan metabolome in urine of patients with acute intermittent porphyria.
TLDR
It is demonstrated that there is an imbalance in the kynurenine metabolic pathway in AIP patients, with an increase of the kwnurenine/tryptophan ratio in urine and a reduction of thekynurenic acid/kynurenines ratio. Expand
Evaluation of markers out of the steroid profile for the screening of testosterone misuse. Part II: Intramuscular administration.
TLDR
Results revealed that resistant glucuronides can be a suitable complement to the current steroid profile and the potential applicability and the limitations of including these markers in the steroid profile are discussed. Expand
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