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Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption
The oocyte is the starting point for a new generation. Most of the machinery for DNA and protein synthesis needed for the developing embryo is made autonomously by the fertilized oocyte. However, inExpand
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The cytochrome P-450 system in fish, aquatic toxicology and environmental monitoring
Aquatic toxicology has been defined as the qualitative and quantitative study of adverse or toxic effects of chemicals and other anthropogenic materials on aquatic organisms. The subject alsoExpand
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Contaminant accumulation and biomarker responses in flounder (Platichthys flesus L.) and Atlantic cod (Gadus morhua L.) exposed by caging to polluted sediments in Sørfjorden, Norway
Flounder (Platichthys flesus L.) and Atlantic cod (Gadus morhua L.) were subjected to caging at polluted sediments in a Norwegian fjord (Sorfjorden) for a period of 3 months. Three caging sites wereExpand
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Induction of hepatic estrogen receptor in juvenile Atlantic salmon in vivo by the environmental estrogen, 4-nonylphenol.
Alkylphenol ethoxylate degradation products such as nonylphenol and octylphenol are shown to have estrogenic effects. Nonylphenol induces synthesis of vitellogenin (a precursor of egg yolk proteins)Expand
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Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (Salmo salar) liver treated with an estrogenic compound, 4‐nonylphenol
Hepatic microsomal biotransformation reactions with xenobiotic and steroid substrates have been investigated in 4-nonylphenol (NP: 1, 5, 25, and 125 mg/kg body weight)-treated juvenile AtlanticExpand
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Route-specific cellular expression of cytochrome P4501A (CYP1A) in fish (Fundulus heteroclitus) following exposure to aqueous and dietary benzo[a]pyrene.
Mummichog (Fundulus heteroclitus), an estuarine, teleost fish, were exposed for 456 hr to environmentally relevant concentrations of aqueous (10 micrograms/liter) and dietary (10 micrograms/g)Expand
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Endocrine Disruptors in the Marine Environment: Mechanisms of Toxicity and their Influence on Reproductive Processes in Fish
  • A. Goksøyr
  • Biology, Medicine
  • Journal of toxicology and environmental health…
  • 1 January 2006
Recent research demonstrated how endocrine-disrupting chemicals (EDCs) may disturb wildlife populations and possibly also represent a human health risk. Much of the focus has been onExpand
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Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).
The pregnane X receptor (PXR) (nuclear receptor NR1I2) is a ligand activated transcription factor, mediating responses to diverse xenobiotic and endogenous chemicals. The properties of PXR in fishExpand
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Fish zona radiata (eggshell) protein: a sensitive biomarker for environmental estrogens.
Environmental estrogens have recently caused great concern because of their ability to mimic natural hormones and influence vital endocrine functions in humans and wildlife. The induction ofExpand
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