• Publications
  • Influence
Evaluation of Prothrombin Complex Concentrate and Recombinant Activated Factor VII to Reverse Rivaroxaban in a Rabbit Model
TLDR
RFVIIa and PCC partially improved laboratory parameters, but did not reverse rivaroxaban induced-bleeding and safety, respectively.
Plasminogen receptors and their role in the pathogenesis of inflammatory, autoimmune and malignant disease
  • A. Godier, B. Hunt
  • Biology, Medicine
    Journal of thrombosis and haemostasis : JTH
  • 1 January 2013
TLDR
This review will discuss currently available information on plasminogen receptors, particularly their mechanisms of action and their roles in inflammatory, autoimmune and malignant disease.
Predictors of pre-procedural concentrations of direct oral anticoagulants: a prospective multicentre study
TLDR
A last DOAC intake 3 days before a procedure resulted in minimal pre-procedural anticoagulant effect for almost all patients and moderate renal impairment, especially in dabigatran-treated patients, and antiarrhythmics in anti-Xa- treated patients should result in a longer DOAC interruption.
Von Willebrand factor as a biological sensor of blood flow to monitor percutaneous aortic valve interventions.
TLDR
Results demonstrate that variations in von Willebrand factor multimeric pattern are highly dynamic, occurring within minutes after changes in blood flow and demonstrates that PFA-CADP can evaluate in real time the results of transcatheter aortic valve procedures.
Tranexamic acid: less bleeding and less thrombosis?
TLDR
If proven, this commentary hypothesizes that TXA has an antithrombotic effect and explores potential mechanisms that include inhibition of the inflammatory effects of plasmin, effects on platelets and effects on factors V and VIII.
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