• Publications
  • Influence
Overexpression of Pectin Methylesterase Inhibitors in Arabidopsis Restricts Fungal Infection by Botrytis cinerea1[C][W]
TLDR
Transformed plants showed a slight but significant increase in root length and were more resistant to the necrotrophic fungus Botrytis cinerea and reduced symptoms caused by the fungus on transgenic plants were related to its impaired ability to grow on methylesterified pectins. Expand
Two Arabidopsis thaliana genes encode functional pectin methylesterase inhibitors1
TLDR
The occurrence of functional PMEIs in Arabidopsis indicates that a mechanism of controlling pectin esterification by inhibition of endogenous PMEs is present in different plant species. Expand
Structural Basis for the Interaction between Pectin Methylesterase and a Specific Inhibitor Protein
TLDR
The three-dimensional structure of the complex between the most abundant PME isoform from tomato fruit and PMEI from kiwi gives an insight into the specificity of the inhibitor toward plant PMEs and the mechanism of regulation of these enzymes. Expand
A glycoprotein inhibitor of pectin methylesterase in kiwi fruit (Actinidia chinensis).
TLDR
Kiwi inhibitor appears to be specific for pectin methylesterase, inasmuch as it was found to be ineffective against other polysaccharide-degrading enzymes, such as polygalacturonase and amylase. Expand
Pectin methylesterase inhibitor.
TLDR
A large protein family including PMEI, invertase inhibitors and related proteins of unknown function has been identified on the basis of amino acid sequence similarity and Cys residues conservation. Expand
A glycoprotein inhibitor of pectin methylesterase in kiwi fruit. Purification by affinity chromatography and evidence of a ripening-related precursor.
TLDR
The results showed that the inhibitor is present in the unripe fruit as an inactive precursor with a higher molecular mass and is transformed into the active protein, most likely by proteinase action, during the course of the ripening process. Expand
Kiwi protein inhibitor of pectin methylesterase
TLDR
The comparison of the sequence of these inhibitors confirms the existence of a novel class of proteins with moderate but significant sequence conservation, comprising plant proteins acting as inhibitors of sugar metabolism enzymes, and probably involved in various steps of plant development. Expand
Tomato pectin methylesterase: Modeling, fluorescence, and inhibitor interaction studies—comparison with the bacterial (Erwinia chrysanthemi) enzyme
TLDR
Fluorescence quenching experiments on tomato PME and on PME‐PMEI complex suggest that tryptophanyl residues present in the active site region are involved in the interaction and that the inhibitor interacts with plant PME at the level of the activeSite, supporting the hypothesis that Asp132 acts as acid/base in the catalytic cycle. Expand
Kiwi protein inhibitor of pectin methylesterase amino-acid sequence and structural importance of two disulfide bridges.
TLDR
The comparison of the sequence of pectin methylesterase inhibitors confirms the existence of a novel class of proteins with moderate but significant sequence conservation, comprising plant proteins acting as inhibitors of sugar metabolism enzymes, and probably involved in various steps of plant development. Expand
CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy
TLDR
Y1 may represent a crucial molecular target for antiangiogenic therapy during cancer progression and it is demonstrated that T22 peptide determines YY1 cytoplasmic accumulation by reducing its phosphorylation via down-regulation of AKT, identifying a crosstalk mechanism involving CXCR4/YY1. Expand
...
1
2
3
4
5
...