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Systematic strategy of prophylactic coronary angiography improves long-term outcome after major vascular surgery in medium- to high-risk patients: a prospective, randomized study.
OBJECTIVES This study was undertaken to determine the impact of a strategy of systematic coronary angiography on immediate- and long-term outcome of patients at medium-high risk who were undergoingExpand
Metabolic and hemodynamic effects of peptide leukotriene C4 and D4 in man
The time course of the effects of intravenous or intracoronary administration of peptide leukotrienes on metabolic parameters and on systemic and coronary hemodynamics was evaluated in 15 patientsExpand
FK506 can activate transforming growth factor-beta signalling in vascular smooth muscle cells and promote proliferation.
AIMS FK506-binding protein (FKBP) 12 is an inhibitor of transforming growth factor (TGF)-beta type I receptors. Several lines of evidence support the view that TGF-beta stimulates vascular smoothExpand
Effects Of Glycoprotein IIb/IIIa Antagonists: Anti Platelet Aggregation And Beyond.
BACKGROUND The use of inhibitors of glycoprotein IIb/IIIa (GPIIb/IIIa) has provided dramatic results in terms of the prevention of acute stent thrombosis and a reduction in major adverse coronaryExpand
Hemodynamic effects of magnesium sulfate on the normal human heart.
Abstract Because of its antiarrhythmic properties,1 parenteral magnesium sulfate has been widely used in the last decades in treating several supraventricular or ventricular arrhythmias2,3 even inExpand
Effects of histamine on coronary hemodynamics in humans: role of H1 and H2 receptors.
To evaluate whether histamine exerts a direct effect on coronary hemodynamics in humans, and to investigate the role played by H1 and H2 receptors in this response, intracoronary saline solution orExpand
Nephropathy after administration of iso-osmolar and low-osmolar contrast media: evidence from a network meta-analysis.
BACKGROUND/OBJECTIVES Contrast-induced nephropathy (CIN) may be a severe complication to the administration of iodine-based contrast media for diagnostic or interventional procedure using radiationExpand
Network meta-analysis on the comparative effectiveness and safety of transcatheter aortic valve implantation with CoreValve or Sapien devices versus surgical replacement
Introduction Surgical replacement for aortic stenosis is fraught with complications in high-risk patients. Transcatheter techniques may offer a minimally invasive solution, but their comparativeExpand
Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.
Tirofiban is a fibrinogen receptor antagonist, generated using the tripeptide Arg-Gly-Asp (RGD) as a template. RGD activates integrin receptors and integrin-mediated signals are necessary for normalExpand