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Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae.
The present study gives specific and useful information about antiprotozoal and cytotoxic activities of some Annonaceae extracts and demonstrates which plants and/or plant parts could be useful in the treatment of leishmaniasis, Chagas' disease and malaria. Expand
Value of the ethnomedical information for the discovery of plants with antifungal properties. A survey among seven Latin American countries.
The findings suggest that the ethnopharmacological approach is useful in guiding the detection of antifungal plants in Latin America mainly for infections in which the pathological expression is obvious and, therefore, the cure can be clearly observed. Expand
Screening of Latin American Plants for Cytotoxic Activity
The SRB cytotoxicity assay was used to screen plant extracts, in a collaborative multinational OAS project involving Argentina, Bolivia, Colombia, Costa Rica, Guatemala, Nicaragua and Panama, against breast, lung, and central nervous system human cancer cell lines, finding Piper barbatum, Senna occidentalis, and Blepharocalyx salicifolius. Expand
Medicinal plants uses of the Tacana, an Amazonian Bolivian ethnic group.
The results of an ethnopharmacological investigation of a Bolivian lowland ethnic group, the Tacana, show that 33% of the approximately 450 different plant species collected during this survey had medicinal uses. Expand
A non-radiolabelled ferriprotoporphyrin IX biomineralisation inhibition test for the high throughput screening of antimalarial compounds.
It is found that methylene blue, thionine, and an extract of plants that contains quinoline derivatives, inhibited the biomineralisation of FP regardless of their intrinsic colour. Expand
A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part I. Evaluation of the antimalarial activity of plants used by the Chacobo Indians.
Thirty extracts of plants traditionally used by the Chacobos, a native community living in the Amazonian part of Bolivia, were screened in vitro and/or in vivo for antimalarial activity, corroborating their traditional uses. Expand
Antimalarial activity of some Colombian medicinal plants.
Antimalarial activity of 10 vegetal extracts, obtained from eight species traditionally used in Colombia to treat malaria symptoms, was evaluated in culture using Plasmodium falciparum chloroquine resistant (FcB2) strain and in vivo on rodent malaria Plas modium berghei. Expand
In vitro immunomodulatory activity of plants used by the Tacana ethnic group in Bolivia.
Ethanolic plant extracts from the pharmacopoeia of the Tacana, an ethnic group from Bolivia, were screened for immunomodulatory activity using complement cascade inhibition and ADP-induced platelet aggregation inhibition assays and inhibition of complement cascade was independent of essential ion complexation. Expand
Leishmanicidal constituents from the leaves of Piper rusbyi.
The kavapyrone (+)-(7 R,8 S)-epoxy-5,6-didehydrokavain (1) and the chalcone flavokavain B (2) were isolated from Piper rusbyi as the bioactive components by bioassay-guided fractionation, using an inExpand
Evaluation of Antileishmanial Activity of Selected Brazilian Plants and Identification of the Active Principles
Plant extracts, fractions, and isolated compounds from some selected Brazilian medicinal plants against strains of promastigotes of Leishmania amazonensis and L. brasiliensis are concluded that the analyzed plants are promising as new and effective antiparasitic agents. Expand