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Potent anti-inflammatory activities of hydroalcoholic extract from aerial parts of Stachys inflata on rats.
Extracts obtained from aerial parts of Stachys inflata have been used in Iranian folk medicine in infective, rheumatic and other inflammatory disorders. In the present study, the anti-inflammatoryExpand
Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats
BackgroundThe rhizomes of Cynodon dactylon are used for the treatment of heart failure in folk medicine. In the present study, we investigated the effects of hydroalcoholic extract of C. dactylonExpand
Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats.
BACKGROUND It has been proposed that metformin exerts protective effects on ischemic hearts. In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters,Expand
Antinociceptive properties of extracts and two flavonoids isolated from leaves ofDanae racemosa
The antinociceptive properties of the hydro-methanolic extract (HME) and two flavonoids isolated fromDanae racemosa have been investigated in several nociceptive rat models. The HME fromD. racemosaExpand
Protective Effects of Methylsulfonylmethane on Hemodynamics and Oxidative Stress in Monocrotaline-Induced Pulmonary Hypertensive Rats
Methylsulfonylmethane (MSM) is naturally occurring organic sulfur that is known as a potent antioxidant/anti-inflammatory compound. The aim of this study was to investigate the effect of MSM onExpand
Effects of extracts from flowering tops of Crataegus meyeri A. Pojark. on ischaemic arrhythmias in anaesthetized rats
Different species of Crataegus, commonly called Hawthorn, were reported to possess wide pharmacological effects on the cardiovascular system. In the present study, chloroform, ethylacetate andExpand
Physicochemical characterization and pharmacological evaluation of ezetimibe-PVP K30 solid dispersions in hyperlipidemic rats.
The aim of this study was to improve the physicochemical properties as well as therapeutic efficacy of ezetimibe (EZT), through preparation of the solid dispersion (SD). SDs were formulated usingExpand
Clavulanic acid exhibits anti-inflammatory effects on carrageenan-induced paw edema model of inflammation in rats
The present study was designed to evaluate the anti -inflammatory effects of clavulanic acid, as a GCPII inhibitor on carrageenan-induced paw edema in rats. Clavulani c cid was administeredExpand
Effects of Endothelin‐1 and the ETA-Receptor Antagonist, BQ123, on Ischemic Arrhythmias in Anesthetized Rats
The effects of intravenous (i.v.) infusions of exogenous endothelin-1 (ET-1, 0.05 and 0.1 nmol/kg/min) on incidence and severity of ventricular arrhythmias during 30-min period of acute myocardialExpand
Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells
Recent epidemiological studies have demonstrated that metformin lowers the risk of several types of cancer in diabetic patients. Matrix metalloproteinases (MMPs) play a crucial role in theExpand