A. Freiburghaus

Publications44
h-index16
Citations897
Highly Influential Citations22
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Metabolism of theophylline by cDNA-expressed human cytochromes P-450.
1. Theophylline metabolism was studied using seven human cytochrome P-450 isoforms (CYPs), namely CYP1A1, 1A2, 2A6, 2B6, 2D6, 2E1 and 3A4, and microsomal epoxide hydroxylase (EH), expressed in human… Expand
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Effect of chemotherapy on the larval mass and the long‐term course of alveolar echinococcosis
The efficacy of long‐term chemotherapy in nonresectable alveolar echinococcosis is debated, particularly because of the difficulty in defining therapeutic success. In this study the effect of… Expand
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In vitro inhibition of midazolam and quinidine metabolism by flavonoids
Studies in humans in vivo have demonstrated that substances found in grapefruit juice may increase the bioavailability of dihydropyridine derivatives as a result of the inhibition of liver enzyme… Expand
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Trends in Influenza Vaccination Coverage Rates in Germany over Six Seasons from 2001/02 to 2006/07
Background and Purpose:Influenza is a considerable health problem all over the world. Vaccination is the most important measure for preventing influenza and reducing morbidity and mortality. The aims… Expand
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Evolution and regression of pancreatic calcification in chronic pancreatitis. A prospective long-term study of 107 patients.
Pancreatic calcifications are virtually pathognomonic of chronic pancreatitis and develop in up to 90% of patients with alcoholic chronic pancreatitis in series with long-term results. We… Expand
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Evolution and regression of pancreatic calcification in chronic pancreatitis: A prospective long-term study of 107 patients
Pancreatic calcifications are virtually pathognomonic of chronic pancreatitis and develop in up to 90% of patients with alcoholic chronic pancreatitis in series with long-term results. We… Expand
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Injection of Microspheres into Pancreatic Arteries Causes Acute Hemorrhagic Pancreatitis in the Rat: A New Animal Model
Alterations in the vascular bed of the pancreas or disturbances of the blood coagulation system are mostly considered to be sequelae of acute pancreatitis, but it seems that impairment of the… Expand
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Biosynthesis of brush border glycoproteins by human small intestinal mucosa in organ culture.
The incorporation of [14C]glucosamine into brush border glycoproteins by human small intestinal mucosa in organ culture has been investigated. The experiments were based on the observations that (1)… Expand
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Protein patterns of brush-border fragments in congenital lactose malabsorption and in specific hypolactasia of the adult.
Brush-border membrane proteins of the small-bowel mucosa were separated on polyacrylamide gels from intestinal biopsy specimens obtained from four children with congenital lactose malabsorption and… Expand
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The brush border membrane in hereditary sucrase—isomaltase deficiency: abnormal protein pattern and presence of immunoreactive enzyme
Abstract. In a child with hereditary sucrase‐isomaltase deficiency immunoreactive enzyme was present in the intact duodenal mucosa. Polyacrylamide gel electrophoresis carried out with membrane… Expand
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