• Publications
  • Influence
Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK.
These evidence-based guidelines have been produced after a literature review of the treatment and prophylaxis of methicillin-resistant Staphylococcus aureus (MRSA) infection. The guidelines wereExpand
Methicillin-resistant Staphylococcus aureus (MRSA): a community-based prevalence survey
TLDR
The prevalence of MRSA colonization in the general adult population in Birmingham appears to be low and 2 of the 4 MRSA carriers reported previous contact with health facilities. Expand
The Antibacterial Activity of Acetic Acid against Biofilm-Producing Pathogens of Relevance to Burns Patients
TLDR
Evidence is provided that acetic acid can inhibit growth of key burn wound pathogens when used at very dilute concentrations, and this novel biocide application offers great promise as a cheap and effective measure to treat infections in burns patients. Expand
Detection of Alloiococcus otitis in mixed bacterial populations from middle-ear effusions of patients with otitis media
TLDR
Many bacterial species were detected by PCR, whereas with culture-based approaches, no bacterial growth was detected for ten of the 12 patients, so the method may have general usefulness in characterising bacterial populations at the site of infection. Expand
British Thoracic Society guidelines on diagnostic flexible bronchoscopy.
TLDR
These guidelines have been developed at the request of the Standards of Care Committee of the British Thoracic Society to advise on bronchoscopy in adults, although the sections of the guidelines concerned with staV safety and instrument decontamination would also be relevant to paediatric flexible bronchoscope. Expand
Guidelines (2008) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom.
These evidence-based guidelines are an updated version of those published in 2006. They have been produced after a literature review of the treatment and prophylaxis of methicillin-resistantExpand
Biocide abuse and antimicrobial resistance--a cause for concern?
  • A. Fraise
  • Biology, Medicine
  • The Journal of antimicrobial chemotherapy
  • 2002
TLDR
Microbial changes that result in resistance to biocides and antibiotics should cause concern, and the possibility of genetic linkage between genes for biocide resistance and those for antibiotic resistance is of equal significance. Expand
Russell, Hugo & Ayliffe's principles and practice of disinfection, preservation & sterilization
TLDR
This 4th edition is divided into two parts: the first on principles and the second on practices, which includes updated material on new and emerging technologies, and concludes with an evaluation of the activity of agents and good manufacturing. Expand
Susceptibility of antibiotic‐resistant cocci to biocides
  • A. Fraise
  • Medicine, Biology
  • Symposium series
  • 1 May 2002
TLDR
Outbreaks of biocide-resistant organisms in hospitals have been described and the genetic mechanism for resistance to quaternary ammonium compounds in Staphylococcus aureus has now been elucidated, and biocide resistance amongst enterococci was demonstrated although there was no clear correlation between biocide and antibiotic resistance. Expand
Genome sequencing and characterization of an extensively drug-resistant sequence type 111 serotype O12 hospital outbreak strain of Pseudomonas aeruginosa.
TLDR
High degrees of sequence similarity were discovered between outbreak isolates collected from recently infected patients, isolates from sinks, an isolate from the sewer, and a historical isolate, suggesting that the ST111 strain has been endemic in the hospital for many years. Expand
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