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Physicochemical Principles of Pharmacy
TLDR
This book brings together the importance of the physicochemical principles in terms of formulation and quality control, and the final goal of pharmacy assistance, which is to ensure the delivery of the drug to its site of action and promote a safe and desired response.
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Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency
TLDR
Measurement of radioactivity of tissues following administration of 100 nm and 1 μm I125‐labelled polystyrene latex particles for 8 days was corroborative although less secure because of the potential lability of the labelled particles.
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Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics.
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Titanium dioxide (rutile) particle uptake from the rat GI tract and translocation to systemic organs after oral administration
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Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60 and 80) and a sorbitan triester (Span 85)
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Surfactant Systems: Their chemistry, pharmacy and biology
1. Surface activity.- 1.1 Amphipathic molecules.- 1.2 Surface activity in aqueous solution.- 1.3 Adsorption at liquid surfaces.- 1.4 Adsorption at solid surfaces.- 1.5 The wettability of solid…
Non-ionic surfactant vesicles (niosomes): Physical and pharmaceutical chemistry
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The Uptake and Translocation of Latex Nanospheres and Microspheres after Oral Administration to Rats
TLDR
A need to re‐examine the possibilities of particulate oral delivery, as well as the potential toxicity of ingested particulates, is demonstrated by unequivocal evidence of uptake and translocation of the particles.
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The preparation and properties of niosomes—non‐ionic surfactant vesicles
TLDR
The physical characteristics of the vesicles were found to be dependent on the method of production and three such methods, based on liposome technology, are described.
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The Oral Absorption of Micro- and Nanoparticulates: Neither Exceptional Nor Unusual
TLDR
It is concluded that there is now no dispute over the fact that particulate uptake does take place, not only via the M-cells in the Peyer's patches and the isolated follicles of the gut-associated lymphoid tissue, but also via the normal intestinal enterocytes.
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