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Occurrence of Sialyltransferase Activity in the Synaptosomal Membranes Prepared from Calf Brain Cortex
The possible occurrence of sialyltransferase activity in the plasma membranes surrounding nerve endings (synaptosomal membranes) was studied, using calf brain cortex. The synaptosomal membranes wereExpand
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Uptake, cell penetration and metabolic processing of exogenously administered GM1 ganglioside in rat brain
GM1 ganglioside, after intravenous injection into rats, is absorbed and taken up by various organs and tissues, including brain. The capacity of brain to take up gangliosides, referred to weightExpand
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Age‐Related Differences in Synaptosomal Peroxidative Damage and Membrane Properties
Abstract: Young, adult, and old rats were used to study the effect of age on the integrity and functioning of brain synaptosomes. An evaluation was made of the differences in lipid composition,Expand
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Interactions of ganglioside GM1 with human and fetal calf sera. Formation of ganglioside-serum albumin complexes.
The interactions of ganglioside GM1 with human and fetal calf sera were studied, the following main results being obtained: (a) GM1, upon incubation with both sera gave origin to two GM1-proteinExpand
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Age‐Related Changes in the Ceramide Composition of the Major Gangliosides Present in Rat Brain Subcellular Fractions Enriched in Plasma Membranes of Neuronal and Myelin Origin
Abstract: Age‐related changes of the ceramide composition of gangliosides were studied in the synaptosomal and myelin fractions from rat brain, carrying plasma membranes of neuronal and glial origin,Expand
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Acidic and neutral sialidase in the erythrocyte membrane of type 2 diabetic patients.
The behavior of the 2 sialidase forms present in the erythrocyte membrane was investigated in 117 subjects with type 2 diabetes mellitus versus 95 healthy controls. A significant increase of theExpand
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Casein phosphopeptide promotion of calcium uptake in HT‐29 cells − relationship between biological activity and supramolecular structure
Casein phosphopeptides (CPPs) form aggregated complexes with calcium phosphate and induce Ca2+ influx into HT‐29 cells that have been shown to be differentiated in culture. The relationship betweenExpand
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Developmental studies of the catabolism of sialocompounds by endogenous neuraminidase in the chick retina.
Abstract The effect of a “particle bound” neuraminidase acting on endogenous sialocompounds (glycoproteins and gangliosides) in chick retina during development has been investigated. The totalExpand
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Release of wheat gluten exorphins A5 and C5 during in vitro gastrointestinal digestion of bread and pasta and their absorption through an in vitro model of intestinal epithelium
Abstract The release of wheat gluten exorphins (GEs) A5, A4, B5, B4, C5, Gd-7 and dGd-7 during in vitro gastrointestinal digestion (GID) of bread and pasta samples has been investigated byExpand
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Incorporation and metabolism of exogenous GM1 ganglioside in rat liver.
The pathways of metabolic processing of exogenously administered GM1 ganglioside in rat liver was investigated at the subcellular level. The GM1 used was 3H-labelled at the level of long-chain baseExpand
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