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Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones.
Environmental iodine deficiency continues to be a significant public health problem worldwide. On the other hand, iodide excess results principally from the use of iodine-containing medicinalExpand
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Silymarin inhibits the progression of fibrosis in the early stages of liver injury in CCl₄-treated rats.
Liver fibrosis, a common condition occurring during the evolution of almost all chronic liver diseases, is the consequence of hepatocyte injury that leads to the activation of Kupffer cells andExpand
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Chemopreventive effects of Calluna vulgaris and Vitis vinifera extracts on UVB-induced skin damage in SKH-1 hairless mice.
Solar ultraviolet radiation (UV) is a major cause of non-melanoma skin cancer in humans. Photochemoprevention with natural products represents a simple but very effective strategy in the managementExpand
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The effects of grape seeds polyphenols on SKH-1 mice skin irradiated with multiple doses of UV-B.
The study investigated the protective activity of red grape seeds (Vitis vinifera L, Burgund Mare variety) (BM) extracts in vivo on multiple doses of ultraviolet radiation (UV)-B-induced deleteriousExpand
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Photodynamic therapy in melanoma--an update.
Melanoma, a cancer that arises from melanocytes is one of the most unresponsive cancers to known therapies. Several studies showed encouraging results of the efficacy of photodynamic therapy (PDT)Expand
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Antioxidant activity of Cornelian cherry (Cornus mas L.) fruits extract and the in vivo evaluation of its anti-inflammatory effects
Abstract The biological activity of Cornus mas fruits (CM) on acute inflammation in relation to the in vitro antioxidant properties was investigated. The in vitro antioxidant activity was evaluatedExpand
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Transient oxidative stress and inflammation after intraperitoneal administration of multiwalled carbon nanotubes functionalized with single strand DNA in rats.
Multi-walled carbon nanotubes (MWCNTs) are widely used for nanotechnology. Their impact on living organisms is, however, not entirely clarified. Oxidative stress and inflammation seem to be the keyExpand
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Metformin plus sorafenib highly impacts temozolomide resistant glioblastoma stem-like cells.
PURPOSE Glioblastoma stem cells (GSCs), responsible for the dismal disease prognosis after conventional treatments, are driven by overactive signaling pathways, such as PI3K/ AKT/mTOR andExpand
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Biphasic pro-melanogenic and pro-apoptotic effects of all-trans-retinoic acid (ATRA) on human melanocytes: time-course study.
BACKGROUND The effects of retinoids on melanogenesis and their mechanism as depigmenting agents in topical therapy have not been fully elucidated. Conflicting data about their impact on melanogenicExpand
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Photoprotective effects of Romanian propolis on skin of mice exposed to UVB irradiation.
We aimed at investigating the antioxidant, antiinflamatory, antiapoptotic and antigenotoxic effects of a Romanian Propolis (RP) extract in two concentrations (RP1 3 mg, respectively RP2 1.5 mgExpand
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