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Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial.
IMPORTANCE Evidence about the efficacy of laparoscopic resection of rectal cancer is incomplete, particularly for patients with more advanced-stage disease. OBJECTIVE To determine whether… Expand
Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
- A. Benson, A. Venook, +30 authors Deborah A. Freedman-Cass
- Journal of the National Comprehensive Cancer…
- 1 March 2017
This portion of the NCCN Guidelines for Colon Cancer focuses on the use of systemic therapy in metastatic disease. Considerations for treatment selection among 32 different monotherapies and… Expand
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.
BACKGROUND Patients with locally advanced rectal cancer who achieve a pathological complete response to neoadjuvant chemoradiation have an improved prognosis. The need for surgery in these patients… Expand
Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018
BackgroundThis is the fourth updated Enhanced Recovery After Surgery (ERAS®) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded… Expand
Long-term Functional Results After Ileal Pouch Anal Restorative Proctocolectomy for Ulcerative Colitis: A Prospective Observational Study
Objective To document functional results in patients treated with an ileal pouch anal anastomosis (IPAA). Summary Background Data The restorative proctocolectomy with IPAA has become the procedure of… Expand
Metaanalysis of trials comparing laparoscopic and open surgery for Crohn’s disease
Background:Several studies in the literature have suggested that laparoscopic surgery for Crohn’s disease is associated with faster postoperative recovery and a morbidity and recurrence rate similar… Expand
EGFR Signals Downregulate Tumor Suppressors miR-143 and miR-145 in Western Diet–Promoted Murine Colon Cancer: Role of G1 Regulators
- H. Zhu, U. Dougherty, +9 authors M. Bissonnette
- Biology, Medicine
- Molecular Cancer Research
- 8 June 2011
Epidermal growth factor receptors (EGFR) contribute to colonic tumorigenesis in experimental models of colon cancer. We previously showed that EGFR was also required for colonic tumor promotion by… Expand
Superior Mesenteric Vein Thrombosis After Colectomy for Inflammatory Bowel Disease
- A. Fichera, L. Cicchiello, D. Mendelson, A. Greenstein, T. Heimann
- Diseases of the colon and rectum
- 1 May 2003
AbstractPURPOSE: Thromboembolism is a significant cause of morbidity and mortality in inflammatory bowel disease. Several prothrombotic conditions have been investigated in inflammatory bowel… Expand
Total mesenteric excision in the surgical treatment of rectal cancer: a prospective study.
BACKGROUND Total mesorectal excision has been advocated in conjunction with low anterior or abdominoperineal resection as the optimal surgical treatment for rectal cancer. It involves removal of the… Expand
Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor (GIST)
- M. Melis, E. Choi, R. Anders, P. Christiansen, A. Fichera
- International Journal of Colorectal Disease
- 26 April 2006
BackgroundLittle is known about the synchronous occurrence of gastrointestinal stromal tumors (GISTs) and other gastrointestinal tumors. We present two cases of an invasive colon cancer with a… Expand