• Publications
  • Influence
Hepatitis B virus a common cause of viral hepatitis consumes a large portion of health resources in developing countries. Data obtained from the Survey of Health and Disease in the Islamic RepublicExpand
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Impact of sleep disturbances in inflammatory bowel disease
Background:  Normal sleep is paramount for a healthy lifestyle and high quality of life. Sleep modulates the immune system and thus affects the course of several chronic inflammatory conditions.Expand
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Atopic irritable bowel syndrome: a novel subgroup of irritable bowel syndrome with allergic manifestations.
BACKGROUND Mast cells have a primary role in atopy. Mast cells may play a unique role in a subgroup of patients with irritable bowel syndrome (IBS). This observation suggests a link between atopicExpand
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Intestinal barrier: An interface between health and disease
Abstract  The intestine constitutes the largest interface between a person and his or her environment, and an intact intestinal barrier is thus essential in maintaining health and preventing tissueExpand
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Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis.
Because only 30% of alcoholics develop alcoholic liver disease (ALD), a factor other than heavy alcohol consumption must be involved in the development of alcohol-induced liver injury. Animal andExpand
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Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease
Background: Overproduction of colonic oxidants contributes to mucosal injury in inflammatory bowel disease (IBD) but the mechanisms are unclear. Our recent findings using monolayers of intestinalExpand
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Reactive oxygen species: are they involved in the pathogenesis of GERD, barrett's esophagus, and the latter's progression toward esophageal cancer?
Reactive oxygen species: are they involved in the pathogenesis of GERD, barrett's esophagus, and the latter's progression toward esophageal cancer?
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Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non‐alcoholic steatohepatitis
Introduction: One of the proposed second hit mechanisms in the pathophysiology of non‐alcoholic steatohepatitis (NASH) is hepatic oxidative stress triggered by elevated levels of endotoxin. WeExpand
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The relevance of sleep abnormalities to chronic inflammatory conditions
Abstract.Sleep is vital to health and quality of life while sleep abnormalities are associated with adverse health consequences. Nevertheless, sleep problems are not generally considered byExpand
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The Role of Protein Kinase C Isoforms in Modulating Injury and Repair of the Intestinal Barrier
Gastrointestinal cells express a diverse group of protein kinase C (PKC) isoforms that play critical roles in a number of cell functions, including intracellular signaling and barrier integrity. PKCExpand
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  • Open Access