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The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV).
- V. Micol, N. Caturla, L. Perez-Fons, V. Mas, L. Pérez, A. Estepa
- Medicine, Biology
- Antiviral research
- 1 June 2005
A commercial plant extract derived from olive tree leaf (Olea europaea) (LExt) and its major compound, oleuropein (Ole), inhibited the in vitro infectivity of the viral haemorrhagic septicaemia virus… Expand
Expression and antiviral activity of a beta-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences.
- A. Falco, V. Chico, L. Marroqui, L. Pérez, J. Coll, A. Estepa
- Biology, Medicine
- Molecular immunology
- 1 February 2008
The in silico identification of a beta-defensin-like peptide sequence (omBD-1) in the rainbow trout (Oncorhynchuss mykiss) database of salmonid EST is reported here. We have studied the transcript… Expand
Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties
Previous research has shown that an antimicrobial peptide (AMP) of the myticin class C (Myt C) is the most abundantly expressed gene in cDNA and suppressive subtractive hybridization (SSH) libraries… Expand
A comparative review on European-farmed finfish RNA viruses and their vaccines.
The diseases causing the highest ecological and socio-economical impacts in European farmed finfish are produced by RNA viruses. Salmon, trout, sea bream, sea bass, carp and turbot, suffer viral… Expand
In vitro and in vivo differential expression of rainbow trout (Oncorhynchus mykiss) Mx isoforms in response to viral haemorrhagic septicaemia virus (VHSV) G gene, poly I:C and VHSV.
- C. Tafalla, V. Chico, L. Pérez, J. Coll, A. Estepa
- Biology, Medicine
- Fish & shellfish immunology
- 1 July 2007
Three different Mx isoforms are known to be present in rainbow trout, however, to date, neither their mechanism of action nor their regulation have been established. Because most previous studies… Expand
Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype
Since adaptive features such as memory were discovered in mammalian innate immunity, interest in the immunological status of primitive vertebrates after infections has grown. In this context, we used… Expand
Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin.
- D. S. Alves, Laura Pérez-Fons, A. Estepa, V. Micol
- Chemistry, Medicine
- Biochemical pharmacology
- 1 August 2004
Commercial plant extracts containing anthraquinones are being increasingly used for cosmetics, food and pharmaceuticals due to their wide therapeutic and pharmacological properties. In this work, the… Expand
Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach
- P. Encinas, M. A. Rodriguez-Milla, B. Novoa, A. Estepa, A. Figueras, J. Coll
- Medicine, Biology
- BMC Genomics
- 27 September 2010
BackgroundDespite rhabdoviral infections being one of the best known fish diseases, the gene expression changes induced at the surface tissues after the natural route of infection… Expand
Rapid detection and quantitation of viral hemorrhagic septicemia virus in experimentally challenged rainbow trout by real-time RT-PCR.
A quantitative real-time RT-PCR (Q-RT-PCR) was developed to detect and determine the amount of viral hemorrhagic septicemia virus (VHSV) in organs of experimentally infected rainbow trout. Primers… Expand
Fast neutralization/immunoperoxidase assay for viral haemorrhagic septicaemia with anti-nucleoprotein monoclonal antibody.
An enzyme-immunohistochemical procedure was employed to facilitate neutralization/diagnostic tests for viral haemorrhagic septicaemia virus (VHSV), a significant pathogen in trout farms throughout… Expand